DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb6c

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001369781.1	Gene:	Serpinb6c / 97848	MGIID:	2145481	Length:	379	Species:	Mus musculus

Alignment Length:	408	Identity:	101/408 - (24%)
Similarity:	177/408 - (43%)	Gaps:	69/408 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLA----- 88
            ::..:.:|...||||||::.....: :|..::|.|..|.::|...||:|||..||...|:
Mouse     1 MMDPLLEANATFALNLLKILGEDRS-KNVFLSPISISSALVMVLLGAKGTTAIQITQALSLGKCS 64

  Fly    89 ------IYVDYPTLRRWYEDVRAYHYLNSEN----TKLFSLRYAYYDDVGDLELVKGYNSVVLEG 143
                  ::..:..|..........:.|.:.|    .|.|.:..::.|...     |.|.:.:.|
Mouse    65 SSEDGDVHQGFQLLLSEVNKTGTQYSLKAANRLFGEKTFDILASFKDSCH-----KFYEAEMEE- 123

  Fly   144 VGEGNVVLREGRPRGVDFDQGAS----IIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYF 204
                           :|| :||:    ..||..:.|.:..||....|..:.:|...::.:...||
Mouse   124 ---------------LDF-KGATEQSRQHINTWVAKKTEDKIKELLSPGTIHSNTPLILVNAVYF 172

  Fly   205 KAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQ--TGKYAYVNNVKGLQADVLELPFGEHELVM 267
            |.||:..|:|..|: |..:....:....|:||.|  |.|..||..:   ...:|.||:..:||.|
Mouse   173 KGKWEKQFNKEDTR-EMPFKVSKNEEKPVQMMFQKSTFKMTYVEEI---STKILLLPYVGNELNM 233

  Fly   268 IVILPKPSQRVSLVLKQLKNLGLHRLLE--ELEASKNESDVEVKLPKFDTRSVLSLEDTVYEAGL 330
            |::||.....:|.|.|::.:   .:.:|  .|:..|.|. |||.||.|.......::|.:.:.|:
Mouse   234 IIMLPDEHVELSTVEKEITH---EKFIEWTRLDRMKGEK-VEVFLPWFKLEENYDMKDVLCKLGM 294

  Fly   331 TDL----RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEG----LPNAVPQKSSGTNNIKFH 387
            ||.    |.:|:.:      :..:|.:||.....:.:.|:|||    ....:..|.|..:...|.
Mouse   295 TDAFEEGRADFSGI------SSKQGLFLSNVIHKSVVEVNEEGSEATAATTIVLKGSSRSTPCFC 353

  Fly   388 INRPFAYLVLQ-RTHKLL 404
            :||||.:.:.. :|:::|
Mouse   354 VNRPFIFFIQHIKTNEIL 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	101/401 (25%)
Serpinb6c	NP_001369781.1	serpin	2..379	CDD:422956	101/407 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020