DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb9g

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_035585.2	Gene:	Serpinb9g / 93806	MGIID:	1919260	Length:	377	Species:	Mus musculus

Alignment Length:	415	Identity:	102/415 - (24%)
Similarity:	164/415 - (39%)	Gaps:	75/415 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYP 94
            :..::.|...||::||::.......:|...:|.|..|.:.|...||:|.|..||...|.:..|
Mouse     1 MDTLSQANGTFAIHLLKVLCQDNPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALHLNPD-- 63

  Fly    95 TLRRWYEDVR-----AYHYLNSENTKLFSLRYA---YYDDVGDL------ELVKGYNSVVLEGVG 145
                  |||.     ..|.||.:|.:.:.|..|   :.::..:|      ..:|.|:|.:.:
Mouse    64 ------EDVHQGFQLLLHNLNKQNNQKYCLTMANRLFVENTCELLPTFKESCLKFYHSEMEQ--- 119

  Fly   146 EGNVVLREGRPRGVDFDQGASII---INDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAK 207
                         :.|.:.|...   ||..:.|.::.||....|:.|.||...::.....||...
Mouse   120 -------------LSFAEAAEESRQHINMWVSKQTNGKIPDLLSKDSVNSQTRLILANALYFHGT 171

  Fly   208 WKYPFDKSQTKVEQFYNAGGSPAGKVEMM--VQTGKYAYVNNVKGLQADVLELPFGEHELVMIVI 270
            |...|:|::|| |..:.........|:||  ..|..:||   ||.:||.||.:|:...:|..:|:
Mouse   172 WCKRFEKNRTK-EMPFKINKKETRPVQMMWREDTLFHAY---VKEIQAQVLVMPYEGIDLNFVVL 232

  Fly   271 LPKPSQRVSLVLKQLKNLGLHRLLEELEA-----SKNESDVEVKLPKFDTRSVLSLEDTVYEAGL 330
            ||.....:|.|...|       ..|:|.|     ..|.::..|.||||..:....:...:...|:
Mouse   233 LPDEGVDISKVENNL-------TFEKLTAWTKPEFMNRTEFHVYLPKFQLQEDYDMNSLLQHLGI 290

  Fly   331 TDLRNEF----ADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQK------SSGTNNIK 385
            .   |.|    |||..|   :......||.:.....:.|:|||...|....      .||.:...
Mouse   291 L---NVFDGSKADLSGM---STKENLCLSEFAHKCVVEVNEEGTEAAAASAVKFIFLCSGPDPET 349

  Fly   386 FHINRPFAYLVLQRTHKLLIHSGVF 410
            |..:.||.:.::.||...::..|.|
Mouse   350 FCADHPFLFFIMHRTTNSILFCGRF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	101/407 (25%)
Serpinb9g	NP_035585.2	SERPIN	4..377	CDD:294093	102/412 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020