Protein Alignment Spn77Bc and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001262103.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 114/472 - (24%)
• Similarity: 188/472 - (39%)
• Gaps: 113/472 - (23%)

  Fly    13 LSLRAHICAN-TVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAE 76
            :|:|..|..: |:|:      :..|..:|..:|.|........:|...:|.|..:.:.|...||.
Human     1 MSIRPQIVISFTMDS------LVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGAR 59

  Fly    77 GTTLKQIRDVLAIYVDY---------PTLRRWYEDVRA-----------------YHYLNSEN-- 113
            ..:..||.:||. :.::         |.|:...:.|.|                 ...||:|:
Human    60 SDSAHQIDEVLH-FNEFSQNESKEPDPCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGL 123

  Fly   114 ---------TKLFSLRYAYYDDV-----GDLE--LVKGYNSVVLEGVGEGNVVLREGRPRGVDFD 162
                     :||..::..|...:     |:.|  :.:.|    |:||    :.........|||.
Human   124 VSCYFGQLLSKLDRIKTDYTLSIANRLYGEQEFPICQEY----LDGV----IQFYHTTIESVDFQ 180

  Fly   163 QG---ASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQF-Y 223
            :.   :...||..::..|..||...:|:.:.|:...::.:...||||||:..||...|....| .
Human   181 KNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCL 245

  Fly   224 NAGGSPAGKVEMMVQTGKY--AYVNNVKGLQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLK 286
            ||..:.:  |:||.|.|.|  .::..||   |.:||:.:.:.:|.|.|:||..|:      ..||
Human   246 NANENKS--VKMMTQKGLYRIGFIEEVK---AQILEMRYTKGKLSMFVLLPSHSK------DNLK 299

  Fly   287 NLGLHRLLEELE------------ASKN--ESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEF 337
            .      |||||            :|:|  |..|.:..|:|.......|...:.:.|:||:.:|.
Human   300 G------LEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDET 358

  Fly   338 -ADLGRMLIPTG---DRGAYLSLYHQFARIVVDEEG-----LPNAVPQKSSGTNNIKFHINRPFA 393
             |||      ||   ....|||.......:.|||.|     ...||..:.|..:.::|:.|.||.
Human   359 RADL------TGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLRSWVEFNANHPFL 417

  Fly   394 YLVL-QRTHKLLIHSGV 409
            :.:. .:|..:|.:..|
Human   418 FFIRHNKTQTILFYGRV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	109/448 (24%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	109/451 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020