Protein Alignment Spn77Bc and SERPINA7

DIOPT Version :9

• Sequence 1: NP_001262103.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 110/450 - (24%)
• Similarity: 184/450 - (40%)
• Gaps: 82/450 - (18%)

  Fly     5 FLGLFGMVLSLRAHI-CA---------NTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAM 59
            ||.|..:||.|.|.| ||         ::....:.|.||:.....||.||.:..:.....:|...
Human     4 FLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVETPDKNIFF 68

  Fly    60 TPFSTWSLMIMFYEGAEGTTLKQIRDVLAI-YVDYPTLRRWYEDVRAYHYLNSENTKLFSLRYAY 123
            :|.|..:.::|...||..:|..:|.:.|.. ..|.|.:    |....:.:|      :.||.:..
Human    69 SPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMV----EIQHGFQHL------ICSLNFPK 123

  Fly   124 YD---DVGDL--------ELVKGYNSVVLEGVGEGNVVLREGRPRGVDFD--QGASIIINDDIDK 175
            .:   .:|:.        .|.|..|.|         ..|.|......||.  ..|...||..::.
Human   124 KELELQIGNALFIGKHLKPLAKFLNDV---------KTLYETEVFSTDFSNISAAKQEINSHVEM 179

  Fly   176 ASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTG 240
            .:..|:.........| |:.|| :...:|||:|..|||.|:|:....:....:...:|.||.|..
Human   180 QTKGKVVGLIQDLKPN-TIMVL-VNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQME 242

  Fly   241 KYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQ----RVSLVLKQLKNLGLHRLLEELEASK 301
            :|.::.::: |...||::.:.::.|.:.| |||..|    ..::..|.||.  .:|||:
Human   243 QYYHLVDME-LNCTVLQMDYSKNALALFV-LPKEGQMESVEAAMSSKTLKK--WNRLLQ------ 297

  Fly   302 NESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLGRMLIPTGDRGAYLS----------- 355
             :..|::.:|||...:...|..|:.:.|:....:|.||...:   |.|.|..||
Human   298 -KGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGL---TEDNGLKLSNRPAGFVLPTQ 358

  Fly   356 LYHQFARIVVDEEGL-PNAVP--QKSSGTNNIKFH----INRPFAYLVLQRTHKLLIHSG 408
            ..|: |.:.:.|:|. ..|||  :.|....|...|    |:|.|..|:|:|:.:.::..|
Human   359 AAHK-AVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLG 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	96/408 (24%)
SERPINA7	XP_006724746.1	alpha-1-antitrypsin_like	46..419	CDD:239011	96/407 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910