DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpini2

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_080736.2	Gene:	Serpini2 / 67931	MGIID:	1915181	Length:	405	Species:	Mus musculus

Alignment Length:	408	Identity:	101/408 - (24%)
Similarity:	172/408 - (42%)	Gaps:	47/408 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SLLQKMTDARL-QFALNLLQMES-THLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIY 90
            |...:.||.:: .||::|.:..| :|.|  |...:|..|..|:.|...||:|...:||...|.:.
Mouse    16 SQTSRATDQKIADFAVDLYKAISLSHKN--NIIFSPLGTTMLLGMVQLGAKGKAQQQILKTLRMR 78

  Fly    91 -----VDYPTLRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVV 150
                 .::..|:..:..:.     ..:....|:|..|.|       |.:|:  :|.|.....|..
Mouse    79 GTPAGEEFSVLKSLFSAIS-----KKKQEFTFNLASALY-------LQEGF--IVKETYLHSNKE 129

  Fly   151 LREGRPRGVDF-DQGASI-IINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFD 213
            ..:...:.||| |...|. .|:..::..:..||.:.:|...|.....::.:...|||..||..|.
Mouse   130 FFQSATKLVDFLDAKTSAQAISTWVESKTDGKIKNMFSEEEFGPLTRLVLVNAIYFKGDWKQKFR 194

  Fly   214 KSQTKVEQFYNAGGSPAGKVEMM--VQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQ 276
            |..|::..|....||.. ||.||  :...:|.|.:. ..:...|||||:...|..:::|||....
Mouse   195 KEDTEMTDFTKKDGSTV-KVPMMKALLRAQYGYFSQ-SSMTCQVLELPYKADEFSLVIILPTEDT 257

  Fly   277 RVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLG 341
            .:..|..|:....:.|...||    :|.:|||.||:|.....|.|::.:|...:|::.:...||.
Mouse   258 SIEEVENQVTAPHVRRWFSEL----HEEEVEVSLPRFKIEQKLDLKEALYSLNVTEIFSGGCDLS 318

  Fly   342 RMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKSSGTN--------NIKFHINRPFAYLVLQ 398
            .:   |.....|:|...|.....::|:|...|.   |:|.|        ..:|..|.||.:::..
Mouse   319 GI---TDSSEVYVSRVMQKVFFEINEDGSEAAA---STGINIPAIMSLTQTQFLANHPFLFILKH 377

  Fly   399 RTHKLLIHSGVFREGEIQ 416
            ...:.::..|...:.:||
Mouse   378 IRTESILFMGKVTDPDIQ 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	96/392 (24%)
Serpini2	NP_080736.2	neuroserpin	23..405	CDD:239003	99/401 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920