DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and serpinh1a

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001103844.1	Gene:	serpinh1a / 555328	ZFINID:	ZDB-GENE-080219-21	Length:	403	Species:	Danio rerio

Alignment Length:	445	Identity:	97/445 - (21%)
Similarity:	165/445 - (37%)	Gaps:	102/445 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 MVLSLRAHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGA 75
            ::|.|.|.:.||.. ..|:...:.|.....|.||.|..:...::||..::|....|.:.:...|.
Zfish     7 LLLCLLATVSANKT-LSSIATTLADNSATLAFNLYQNMAKDKDIENILISPVVVASSLGLVALGG 70

  Fly    76 EGTTLKQIRDVLA-----------------IYVDYPTLRR--WYEDVRAY---------HYLNSE 112
            :..|..|::.||:                 ..|..|..|.  |....|.|         .:|.|
Zfish    71 KSNTASQVKTVLSAASVKDEQLHSGLSELLTEVSNPKARNVTWKISNRFYGPSSVSFVDDFLKS- 134

  Fly   113 NTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKAS 177
                 |.::..||                    ...:..|:.|        .|...|||...|::
Zfish   135 -----SKKHYNYD--------------------HSKINFRDKR--------SAVKAINDWASKST 166

  Fly   178 HAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAG---------KV 233
            ..|:  ....:....|...:.|...::|..|.          |||::......|         .|
Zfish   167 DGKL--PEVTKDVEKTDGAMIINAMFYKPHWN----------EQFHHKMVDNRGFLVHRSFTVSV 219

  Fly   234 EMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELE 298
            .||.:||.|.::::... :..|||:|.......:::|:|...:.:..|.|.|....|:..:..:|
Zfish   220 PMMHRTGIYGFLDDTTN-KLLVLEMPLAHKMSSLVLIMPYHVESLERVEKLLTRQQLNTWVSAME 283

  Fly   299 ASKNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEF-ADLGRMLIPTGDRGAYLSLYHQFAR 362
                :..|.:.|||.......:|:..:.|.|||:..::. |||..:   :|.:..|||.....:.
Zfish   284 ----QKAVAISLPKVSMEVSHNLQKHLAELGLTEAVDKAKADLSNI---SGKKDLYLSNVFHASA 341

  Fly   363 IVVDEEGLPNAVPQKS-SGTNNIK----FHINRPFAYLVL-QRTHKLLIHSGVFR 411
            :..|.||.|   |..| .||:.:|    |:.:.||.:||. .:|:.:|....:.|
Zfish   342 MEWDTEGNP---PDTSIFGTDQLKNPKLFYADHPFVFLVKDNKTNSILFMGRLIR 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	89/417 (21%)
serpinh1a	NP_001103844.1	SERPIN	26..391	CDD:294093	90/421 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110