Protein Alignment Spn77Bc and SERPINE2

DIOPT Version :10

• Sequence 1: NP_649207.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 84/363 - (23%)
• Similarity: 148/363 - (40%)
• Gaps: 51/363 - (14%)

  Fly    55 ENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYPTLRRWYEDVRAYHYLNSENTKLFSL 119
            :|..::|....|::.|...||:|.|.||:..|:...|:           .....|...|..:.|.
Human    61 DNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVN-----------GVGKILKKINKAIVSK 114

  Fly   120 RYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGASII--INDDIDKASHAKIF 182
            :......|.:...||..:.:.:..|.....|. :...|.|:|:..||..  ||..:...:...|.
Human   115 KNKDIVTVANAVFVKNASEIEVPFVTRNKDVF-QCEVRNVNFEDPASACDSINAWVKNETRDMID 178

  Fly   183 SSYSRRSFNSTVT-VLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQ-----TGK 241
            :..|....:..:| ::.:...|||..||..|....||...|..|.|. :.:|.|:.|     .|.
Human   179 NLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGK-SYQVPMLAQLSVFRCGS 242

  Fly   242 YAYVNNVKGLQADVLELPFGEHELVMIVILP-KPSQRVSLVLKQLKNLGLHRLLEELEASKNESD 305
            .:..|:   |..:.:|||:....:.|::.|| :.|..:|.::..:....:...:..:...:
Human   243 TSAPND---LWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKR---- 300

  Fly   306 VEVKLPKFDTRSVLSLEDTVYEAGLTDL----RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVD 366
            |:|.||||...:...|::.:...|:||:    :..||.     |.||....::|...|.|:|.|.
Human   301 VQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAK-----ITTGSENLHVSHILQKAKIEVS 360

  Fly   367 EEGLPNAVPQKSSGTNNIK--------FHINRPFAYLV 396
            |:|     .:.|:.|..|.        |.::|||.:.:
Human   361 EDG-----TKASAATTAILIARSSPPWFIVDRPFLFFI 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_649207.1	serpin	33..412	CDD:476815	84/363 (23%)
SERPINE2	XP_005246698.1	serpinE2_GDN	33..408	CDD:381039	84/363 (23%)