Protein Alignment Spn77Bc and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001262103.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 83/376 - (22%)
• Similarity: 153/376 - (40%)
• Gaps: 40/376 - (10%)

  Fly    36 ARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYPTLRRWY 100
            :|..|..:|.:..::....::...:|.|....:.|...||..:|..||.:.|.:.:...:.:..:
Human    44 SRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELH 108

  Fly   101 EDVRAYHYLNSENTK-----LFSLRYAYYDD-VGDLE--LVKGYNSVVLEGVGEGNVVLREGRPR 157
               |.:..|..|..:     ..||..|.:.| |.||:  .|....:          :.|.:..|.
Human   109 ---RGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKT----------LYLADTFPT 160

  Fly   158 GVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQF 222
            ......||...|||.:.|.:..||....  ::.:|...|:.:...:|||||:..|:...|:.:.|
Human   161 NFRDSAGAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDF 223

  Fly   223 YNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLKN 287
            | .......:|.||.:..:|.|:.: :.|...|:.:|: :.....:.|||...:     ::|::|
Human   224 Y-VTSETVVRVPMMSREDQYHYLLD-RNLSCRVVGVPY-QGNATALFILPSEGK-----MQQVEN 280

  Fly   288 LGLHRLLEELEASKNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLGRMLIPTGDRGA 352
            ....:.|.:......:..:|:.||||.......||..:...|::::....|||..  |.......
Human   281 GLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSG--ISNHSNIQ 343

  Fly   353 YLSLYHQFARIVVDEEGLPNAVPQ------KSSGTNNIKFHINRPFAYLVL 397
            ...:.|: |.:.|||.|...|...      :|:..|:.:...||||...::
Human   344 VSEMVHK-AVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	83/376 (22%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	83/376 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910