DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and serpine2

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_956478.1	Gene:	serpine2 / 393153	ZFINID:	ZDB-GENE-040426-848	Length:	395	Species:	Danio rerio

Alignment Length:	416	Identity:	96/416 - (23%)
Similarity:	175/416 - (42%)	Gaps:	53/416 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VLSLRAHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAE 76
            ||.|...:..:...:.|...:.:|..||..:.:||..:.    ||..::|....|::.|...||.
Zfish     9 VLFLLCSVSVSQSQSSSYGARGSDLGLQVFMQVLQDRAQ----ENVLLSPHGVASVLGMLLPGAH 69

  Fly    77 GTTLKQIRDVLAIYVDYPTLRRWYEDVRAYH--YLNSENTKLFSLRYAYYDDVGDLELVKGYNSV 139
            |.|.:|:.:.|....:.|     |:.:|..|  .....|..:.::..|.:.:.| ..:.:.:.|.
Zfish    70 GDTRRQLLNGLKYKKNGP-----YKMLRKLHKSLTTKSNADIVTIANALFPNEG-FSMKEDFLSA 128

  Fly   140 VLEGVGEGNVVLREGRPRGVDFD--QGASIIINDDIDKASHAKIFSSYSRRSFNSTVT-VLGITV 201
            ..|.      .|.|.  ..||:.  :.|:..|||.:..::..:|.|..:...|::.:| ::.:..
Zfish   129 NREN------FLCES--HSVDYSDPEAAAQSINDWVKNSTKGQIPSVVTADMFDTALTRLVAVNS 185

  Fly   202 SYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKY--AYVNNVKGLQADVLELPFGEHE 264
            .:||..||..|....||...| .||.....||.||.|...:  ...:...|.:..|:|||:..:.
Zfish   186 IFFKGLWKSRFQPQSTKPRSF-TAGDGNTYKVPMMSQLSVFNMGQASTPDGQKYIVIELPYHGNS 249

  Fly   265 LVMIVILP-KPSQRVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFDTRSVLSLEDTVYEA 328
            :.|.:.|| :.|..:|.:|..:..    ..::......|...:.:.:|||.....|.||..:...
Zfish   250 MSMFIALPTEDSTPLSSILPHIST----NTIQSWTKLMNPRRMRLLMPKFTVEQELDLETPLKAL 310

  Fly   329 GLTDL--RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKSSGTNNIKFH---- 387
            |:.|:  :|: ||...:    .....|:|...|.|:|.|:|:|      .|:|.|.::..|
Zfish   311 GIKDIFDQNK-ADFRHL----SSESIYVSKALQKAKIEVNEDG------TKASATTSVILHARSS 364

  Fly   388 -----INRPFAYLVLQRTHKLLIHSG 408
                 ::|||.:|:...:...::.:|
Zfish   365 PPWVTVDRPFLFLIRHNSSGTILFAG 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	91/392 (23%)
serpine2	NP_956478.1	PAI-1_nexin-1	26..395	CDD:239006	92/399 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920