DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinc1

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001012027.1	Gene:	Serpinc1 / 304917	RGDID:	1307404	Length:	465	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	104/417 - (24%)
Similarity:	176/417 - (42%)	Gaps:	70/417 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TKSLLQKMTDARLQFALNLLQMESTHL-----NLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRD 85
            |...:.:::.|..:||.|..|    ||     :.:|..::|.|..:...|...||...||||:.:
  Rat    77 TNRRVWELSKANSRFATNFYQ----HLADSKNDNDNIFLSPLSISTAFAMTKLGACNNTLKQLME 137

  Fly    86 VLAIYVDYPTLRRWYED----------VRAYHYLNSEN-----TKLF---SLRY-AYYDDVGDLE 131
            |.    .:.|:.....|          .|.|...|..:     .:||   ||.: ..|.||.  |
  Rat   138 VF----KFDTISEKTSDQIHFFFAKLNCRLYRKANKSSNLVSANRLFGDKSLTFNESYQDVS--E 196

  Fly   132 LVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQG---ASIIINDDIDKASHAKIFSSYSRRSFNST 193
            :|.|                  .:.:.:||.:.   :.:.||:.:...:..:|.....:.:.:..
  Rat   197 IVYG------------------AKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAIDEL 243

  Fly   194 VTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLEL 258
            ..::.:...|||..||..|....|:.|.|:...|... .|.||.|.||:.|....:|.|  |||:
  Rat   244 TALVLVNTIYFKGLWKSKFSPENTRKEPFHKVDGQSC-LVPMMYQEGKFKYRRVGEGTQ--VLEM 305

  Fly   259 PFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFDTRSVLSLED 323
            ||...::.|::|||||.:.::.|.::|....|...|:||    :|..:.|.:|:|......||::
  Rat   306 PFKGDDITMVLILPKPEKSLAKVEQELTPELLQEWLDEL----SEVMLVVHVPRFRIEDSFSLKE 366

  Fly   324 TVYEAGLTDLRNEFADLGRMLIPTGDRGAYLS-LYHQFARIVVDEEGLPNA------VPQKSSGT 381
            .:.:.||.||.:........:|..|....::| .:|: |.:.|:|||...|      :..:|...
  Rat   367 QLQDMGLVDLFSPEKSQLPGIIAEGRDDLFVSDAFHK-AFLEVNEEGSEAAASTSVVITGRSLNP 430

  Fly   382 NNIKFHINRPFAYLVLQRTHKLLIHSG 408
            :.:.|..||||..|:.:.....:|..|
  Rat   431 SRVTFKANRPFLVLIREVALNTIIFMG 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	103/407 (25%)
Serpinc1	NP_001012027.1	antithrombin-III_like	80..459	CDD:239000	103/414 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920