DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	92/423 - (21%)
Similarity:	169/423 - (39%)	Gaps:	60/423 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RAHICANTVDTK-SLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTT 79
            |...||.:...: :::..:.:....|||.||:..|.. :..|..::|.|..:.:.|.:.||:|.|
  Rat     7 RPGCCAGSGGYRFTIMDHLQEGNGIFALKLLKTLSED-SSNNIFLSPISISAALTMVFMGAKGMT 70

  Fly    80 LKQIRDVLA-----------IYVDYPTLRRWYEDVRAYHYLNSENTKLFSLR----YAYYDDVGD 129
            ..|:...|:           ::..:.:|..........:.|.:.| :||..:    .|.:.|.
  Rat    71 ASQMVQTLSLDKCSGNGGGDVHQGFQSLLAEVNKTGTQYLLKTAN-RLFGEKTCDILASFKDA-- 132

  Fly   130 LELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTV 194
              ..|.|.:.:.|...:|:.  .:.|.|           ||..:.|.:..||....:....:...
  Rat   133 --CRKFYEAEMEELDFKGDT--EQSRQR-----------INTWVAKKTEDKIKELLAPGIVDPDT 182

  Fly   195 TVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMV--QTGKYAYVNNVKGLQADVLE 257
            .::.:...|||..|...|:|..|: |:.:....:....|:||.  .|.|..|:..:   ...:|.
  Rat   183 VLVLVNAIYFKGNWDKQFNKEHTR-EKPFKVSKTEEKPVQMMFMKSTFKMTYIGEI---FTKILL 243

  Fly   258 LPFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASK-NESDVEVKLPKFDTRSVLSL 321
            ||:..:||.||::||.....:..|.|:|.   ..:.:|...... :|.:|||.||:|.......:
  Rat   244 LPYAGNELNMIIMLPDEHIELKTVEKELT---YEKFIEWTRLDMLDEEEVEVFLPRFKLEENYDM 305

  Fly   322 EDTVYEAGLTDL----RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKSSGTN 382
            :..:.:.|:||.    |.:|:.:      ...:|.:||.....|.:.|:|||........|:.|.
  Rat   306 KVVLGKLGMTDAFMEGRADFSGI------ASKQGLFLSKVIHKAFVEVNEEGTEAVAATGSTITM 364

  Fly   383 NI-----KFHINRPFAYLVLQRTHKLLIHSGVF 410
            ..     :|..:.||.:.:.....|.::..|.|
  Rat   365 RCLRFTPRFLADHPFLFFIQHVKTKGILFCGRF 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	88/400 (22%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	89/405 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020