Protein Alignment Spn77Bc and Serpine1

DIOPT Version :10

• Sequence 1: NP_649207.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_036752.2
• Gene: Serpine1 / 24617
• RGDID: 3249
• Length: 402
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 93/434 - (21%)
• Similarity: 175/434 - (40%)
• Gaps: 64/434 - (14%)

  Fly     1 MKLGFLGLFGMVLSLRAHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTW 65
            :.||.:.:||...       |:.:......|:.|:..::...:::|....    .|...:|:...
  Rat    10 LTLGLVLVFGKGF-------ASPLPESHTAQQATNFGVKVFQHVVQASKD----RNVVFSPYGVS 63

  Fly    66 SLMIMFYEGAEGTTLKQIRDVLAIYVD----YPTLRRWYEDVRAYHYLNSENT--KLFSLRYAYY 124
            |::.|......|.|.:||:|.:...:.    .|.||:..:::......|..:|  .:|..|
  Rat    64 SVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQR---- 124

  Fly   125 DDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFD--QGASIIINDDIDKASHAKIFSSYSR 187
                |||||:|:.....:        |.....:.|||.  :.|..||||.:::.:...|....::
  Rat   125 ----DLELVQGFMPHFFK--------LFRTTVKQVDFSEMERARFIINDWVERHTKGMISDLLAK 177

  Fly   188 RSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYV--NNVKG 250
            .:.|....::.:...||..:||.||.::.|....|:.:.||.. .|.||.|..|:.|.  ....|
  Rat   178 GAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTI-SVPMMAQNNKFNYTEFTTPDG 241

  Fly   251 LQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFDT 315
            .:.|:||||:....|.|.:..|...   .:.|..:.|:....|:.:.:::.......:.||||..
  Rat   242 HEYDILELPYHGETLSMFIAAPFEK---DVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSL 303

  Fly   316 RSVLSLEDTVYEAGLTDL----RNEFADLGRMLIPTGDRGAYLSLYH--QFARIVVDEEGLPNA- 373
            .:.:.|...:.:.|:||:    :.:|..|...        ..||:..  |..:|.|:|.|...:
  Rat   304 ETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQ--------EQLSVAQALQKVKIEVNESGTVASS 360

  Fly   374 -----VPQKSSGTNNIKFHINRPFAYLVLQRTHKLLIHSGVFRE 412
                 |..:.:.|..:   ::|.|.::|.....:.::..|...|
  Rat   361 STAILVSARMAPTEMV---LDRSFLFVVRHNPTETILFMGQLME 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_649207.1	serpin	33..412	CDD:476815	86/400 (22%)
Serpine1	NP_036752.2	serpin	29..402	CDD:476815	88/408 (22%)