DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_035590.1	Gene:	Serpinb9d / 20726	MGIID:	894667	Length:	377	Species:	Mus musculus

Alignment Length:	410	Identity:	98/410 - (23%)
Similarity:	162/410 - (39%)	Gaps:	65/410 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYP 94
            :..::.|...||::||::.......||...:|.|..|.:.|...||:|.|:.||...|.:..|
Mouse     1 MNTLSQANGTFAIHLLKVLCQDNPSENVCFSPMSISSALAMVLLGAKGNTVTQICQALHLNPD-- 63

  Fly    95 TLRRWYEDVR-----AYHYLNSENTKLFSLRYA---YYDDVGDL------ELVKGYNSVVLEGVG 145
                  |||.     ..|.||..|.:.:.|..|   :.::..:|      ..:|.|:|.:.:
Mouse    64 ------EDVHQGFQLLLHNLNKPNNQKYCLTMANRLFVENTCELLPTFKESCLKFYHSEMEQ--- 119

  Fly   146 EGNVVLREGRPRGVDFDQGASII---INDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAK 207
                         :.|.:.|...   ||..:.|.::.||.....:.|.:|...::.....||:..
Mouse   120 -------------LSFAEAAEESRQHINMWVSKQTNGKIPDLLPKDSIDSQTRLILANALYFQGT 171

  Fly   208 WKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILP 272
            |...|:|..|| |..:.........|:||.|..:: |...||.:||.||.:|:...:|..:|:||
Mouse   172 WYKLFEKDSTK-EMPFKINKKETRPVQMMWQEDRF-YHAYVKEIQAQVLVMPYEGIDLSFVVLLP 234

  Fly   273 KPSQRVSLVLKQLKNLGLHRLLEELEA-----SKNESDVEVKLPKFDTRSVLSLEDTVYEAGLTD 332
            .....:|.|...|       ..|:|.|     ..|..::.|.||||..:....:...:...|:.|
Mouse   235 DKGVDISKVENNL-------TFEKLTAWTKPDFMNGIELHVYLPKFQLQEDYDMNSLLQHLGILD 292

  Fly   333 L-RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVP------QKSSGTNNIKFHINR 390
            : ....|||..|  .|.:.....:..|:.. :.|:|||...|..      |...|:....|..:.
Mouse   293 VFDGSKADLSGM--STKENLCLSNFVHKCV-VEVNEEGTEAAAATAGKTIQCCLGSYPQTFCADH 354

  Fly   391 PFAYLVLQRTHKLLIHSGVF 410
            ||.:.::..|...::..|.|
Mouse   355 PFLFFIMHSTTNSILFCGRF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	97/402 (24%)
Serpinb9d	NP_035590.1	serpin	1..377	CDD:393296	98/410 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020