DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb9b

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_035582.1	Gene:	Serpinb9b / 20706	MGIID:	894668	Length:	377	Species:	Mus musculus

Alignment Length:	415	Identity:	96/415 - (23%)
Similarity:	166/415 - (40%)	Gaps:	75/415 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVD-- 92
            :..:::|...||::||:|.......:|...:|.|..|.:.|...||:..|..||...|.:..:
Mouse     1 MSTLSEANGTFAIHLLKMLCQSNPSKNVCFSPVSISSALAMVLLGAKEQTAVQISQALGLKKEKG 65

  Fly    93 -----YPTLRRWYEDVRAYHYLNSENTKLFSLR------------YAYYDDVGDLELVKGYNSVV 140
                 ...||:..:..|.|..:.:  .:||:.:            :.:||  .::|.|..:.:.|
Mouse    66 IHQGFLKLLRKLNKPDRKYSLIVA--NRLFADKTCEVLQTFKESCFRFYD--SEMEQVNFFKAAV 126

  Fly   141 LEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFK 205
                        |.|.           .||..:.|.:..||....:..|.|....::.:...|||
Mouse   127 ------------ESRQ-----------CINTWVSKQTEGKIPELLADDSVNFQTRLVLVNALYFK 168

  Fly   206 AKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTG--KYAYVNNVKGLQADVLELPFGEHELVMI 268
            ..|...|.|..|:...|| ........|:||.||.  .:|:|:.   |.|.:|.:|:...||.::
Mouse   169 GMWACQFCKESTREMPFY-INKDEKRPVQMMCQTDTFMFAFVDE---LPARLLIMPYEGMELSLM 229

  Fly   269 VILPKPSQRVSLVLKQLKNLGLHRLLEELEA-SKNE----SDVEVKLPKFDTRSVLSLEDTVYEA 328
            |:||:....:|.|...|       ..|:|.| :|.:    ::|:|.||||..:....::..:...
Mouse   230 VLLPEKGVDLSKVENDL-------TFEKLIAWTKPDIMWSTEVKVFLPKFKLQEDYEMKSVLQCL 287

  Fly   329 GLTDL-RNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKSSGTNNI-------K 385
            |:.|: ..|.|||..|   :.:|...||.:...:.:.|:|||...|....:.|...:       .
Mouse   288 GIVDVFEKEKADLSAM---SPERNLCLSKFIHKSVVEVNEEGTEAAAASSAEGIIPLCLGGGPSW 349

  Fly   386 FHINRPFAYLVLQRTHKLLIHSGVF 410
            |..:.||.:.:.......::..|.|
Mouse   350 FCADHPFLFFIRHNQTNSILFCGRF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	95/407 (23%)
Serpinb9b	NP_035582.1	SERPIN	4..377	CDD:294093	96/412 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020