DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpinb3a

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_033152.3	Gene:	Serpinb3a / 20248	MGIID:	3573933	Length:	387	Species:	Mus musculus

Alignment Length:	415	Identity:	107/415 - (25%)
Similarity:	180/415 - (43%)	Gaps:	86/415 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DARLQFALNLLQM--ESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYPTLR 97
            :|..:|.|.|.:.  ||.:    |...:|.|..:.:.|...||:|.|.|||..||..   ..|.:
Mouse     6 EATTKFTLELYRQLRESDN----NIFYSPISMMTALAMLQLGAKGNTEKQIEKVLQF---NETTK 63

  Fly    98 RWYEDVRAYHYLNSEN---------TKLFSLRYAYYDDVGDLEL------VKGYNSV--VLEGVG 145
            :..|  ::.|..:.||         |:|.....||     ||:.      .||:..|  .||.:.
Mouse    64 KTTE--KSAHCHDEENVHEQFQKLMTQLNKSNDAY-----DLKAANSIYGAKGFPFVQTFLEDIK 121

  Fly   146 E---GNVVLREGRPRGVDFDQGASII---INDDIDKASHAKIFSSYSRRSFN-STVTVLGITVSY 203
            |   .||       ..:||:..|...   ||..::..::.||...:...|.| ||:.|| :...|
Mouse   122 EYYQANV-------ESLDFEHAAEESEKKINSWVESQTNGKIKDLFPNGSLNRSTIMVL-VNAVY 178

  Fly   204 FKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMI 268
            ||.:|.:.||:..|..|:|: ...:.:..|:||.|..::.:: .::.:||.::|:|:...||.||
Mouse   179 FKGQWNHKFDEKHTTEEKFW-LNKNTSKPVQMMKQNIEFNFM-FLEDVQAKIVEIPYKGKELSMI 241

  Fly   269 VILPKPSQRVSLVLKQLKNLGLHRLLEELEASK----------NESDVEVKLPKFDTRSVLSLED 323
            |:||            ::..||.:|.|:|.|.|          :.:::.:.||:|.......|..
Mouse   242 VLLP------------VEINGLKQLEEQLTADKLLEWTRAENMHMTELYLSLPRFKVDEKYDLPI 294

  Fly   324 TVYEAGLTDLRN-EFADLGRMLIPTGDRGAYLS--LYHQFARIVVDEEGLPNAVP-----QKSSG 380
            .:...|:.|..: :.||...|   :..:|..:|  |:..|  :.|:|||...|..     ..:|.
Mouse   295 PLEHMGMVDAFDPQKADFSGM---SSTQGLVVSKVLHKSF--VEVNEEGTEAAAATGVEVSLTSA 354

  Fly   381 TNNIKFHINRPFAYLVLQR-THKLL 404
            .....|..:.||.:.::.| |:.:|
Mouse   355 QIAEDFCCDHPFLFFIIHRKTNSIL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	107/414 (26%)
Serpinb3a	NP_033152.3	SERPIN	5..387	CDD:294093	107/415 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020