Protein Alignment Spn77Bc and SERPINB1

DIOPT Version :9

• Sequence 1: NP_001262103.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_109591.1
• Gene: SERPINB1 / 1992
• HGNCID: 3311
• Length: 379
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 101/413 - (24%)
• Similarity: 172/413 - (41%)
• Gaps: 69/413 - (16%)

  Fly    30 LQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYP 94
            :::::.|..:|||:|....|.:....|..::|||..|.|.|.:.|..|.|..|:....    .:.
Human     1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTF----HFN 61

  Fly    95 TLRRWYEDVRA-YHYLNSENTK-----LFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLRE 153
            |:    |:|.: :..||::..|     :..|....|.:       |.||.:       ...::..
Human    62 TV----EEVHSRFQSLNADINKRGASYILKLANRLYGE-------KTYNFL-------PEFLVST 108

  Fly   154 GRPRG-----VDF---DQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKY 210
            .:..|     |||   .:.|...||..:...:..||....:....::...::.:...|||..||.
Human   109 QKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKD 173

  Fly   211 PFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPS 275
            .|.|..|....| .........|:||.|..|:|| ..::.|:..|||||:...||.|:::||...
Human   174 KFMKEATTNAPF-RLNKKDRKTVKMMYQKKKFAY-GYIEDLKCRVLELPYQGEELSMVILLPDDI 236

  Fly   276 QRVSLVLKQLKNLGLHRLLEEL-EASKNES----DVEVKLPKFDTRSVLSLEDTVYEAGLTDLRN 335
            :..|..||:::.   ...||:| |.:|.|:    :|.|.||:|......:|...:...|:.||.|
Human   237 EDESTGLKKIEE---QLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFN 298

  Fly   336 EF-ADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNA------------VPQKSSGTNNIKFH 387
            .. |||..|   :|.|..::|.....:.:.|:|||...|            :|:::       |.
Human   299 SSKADLSGM---SGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEEN-------FT 353

  Fly   388 INRPFAYLVLQRTHKLLIHSGVF 410
            .:.||.:.:...:...::..|.|
Human   354 ADHPFLFFIRHNSSGSILFLGRF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	100/405 (25%)
SERPINB1	NP_109591.1	SERPIN	4..379	CDD:294093	101/410 (25%)
		CARD-binding motif (CBM). /evidence=ECO:0000269|PubMed:30692621	351..379		5/33 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920