DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpine1

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_032897.2	Gene:	Serpine1 / 18787	MGIID:	97608	Length:	402	Species:	Mus musculus

Alignment Length:	437	Identity:	99/437 - (22%)
Similarity:	169/437 - (38%)	Gaps:	77/437 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LGLF-----GMVLSLR-AHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFST 64
            |||.     |..|.|| :|......|              |.:.:.|.........|...:|:..
Mouse    12 LGLVLVSGKGFTLPLRESHTAHQATD--------------FGVKVFQQVVQASKDRNVVFSPYGV 62

  Fly    65 WSLMIMFYEGAEGTTLKQIRDVLAIYVDYP----TLRRWYEDVRAYHYLNSENT--KLFSLRYAY 123
            .|::.|......|.|.:||:|.:...|:..    .||:..:::......|..:|  .:|..|
Mouse    63 SSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQR--- 124

  Fly   124 YDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFD--QGASIIINDDIDKASHAKIFSSYS 186
                 |||||:|:.....:        |.:...:.|||.  :.|..||||.:::.:...|....:
Mouse   125 -----DLELVQGFMPHFFK--------LFQTMVKQVDFSEVERARFIINDWVERHTKGMISDLLA 176

  Fly   187 RRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYV--NNVK 249
            :.:.:....::.:...||..:||.||.::.|....|:.:.||.. .|.||.|:.|:.|.  ....
Mouse   177 KGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTV-SVPMMAQSNKFNYTEFTTPD 240

  Fly   250 GLQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFD 314
            ||:.||:|||:....|.|.:..|...   .:.|..|.|:....|:.:.:.:.......:.||||.
Mouse   241 GLEYDVVELPYQGDTLSMFIAAPFEK---DVHLSALTNILDAELIRQWKGNMTRLPRLLILPKFS 302

  Fly   315 TRSVLSLEDTVYEAGLTDLRN----EFADLGRMLIPTGDRGAYLSLYH--QFARIVVDEEGLPNA 373
            ..:.:.|...:.:.|:.|:.:    :|..|...        ..||:..  |..||.|:|.|
Mouse   303 LETEVDLRGPLEKLGMPDMFSATLADFTSLSDQ--------EQLSVAQALQKVRIEVNESG---- 355

  Fly   374 VPQKSSGTNNI--------KFHINRPFAYLVLQRTHKLLIHSGVFRE 412
             ...||.|..:        :..|:|.|.::|.....:.::..|...|
Mouse   356 -TVASSSTAFVISARMAPTEMVIDRSFLFVVRHNPTETILFMGQVME 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	89/397 (22%)
Serpine1	NP_032897.2	SERPIN	29..402	CDD:294093	92/420 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920