DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn77Bc and Serpinb5

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_476449.2	Gene:	Serpinb5 / 116589	RGDID:	69342	Length:	375	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	89/397 - (22%)
Similarity:	159/397 - (40%)	Gaps:	53/397 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYPTLRRWY 100
            |...||:.|.:.........|...:|....:.:.:...||:|.|..:|..||           .:
  Rat     7 ANSAFAVELFKQLCEKEPAGNILFSPICLSTSLSLAQVGAKGDTANEIGQVL-----------HF 60

  Fly   101 EDVR----AYHYLNSENTKLFSLRYAYYDDVGDLELVKGY---NSVVLEGVGEGNVVLREGRP-- 156
            |:|:    .:..:.|:..||.|    :|    .|:|:|..   .|:.|    ....:....||
  Rat    61 ENVKDVPFGFQTITSDVNKLSS----FY----SLKLIKRLYIDKSLNL----STEFISSTKRPYA 113

  Fly   157 ---RGVDF------DQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPF 212
               ..|||      .:|.   ||..|.:.:...........|.:....:|.:..:||..||...|
  Rat   114 NELETVDFKDKLEETKGQ---INSSIKELTDGHFEDILPENSISDQTKILVVNAAYFVGKWMKKF 175

  Fly   213 DKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQR 277
            .:|:|| |..:....:....|:||.....:. :.|:..:...::||||....|.|:::|||..:.
  Rat   176 PESETK-ECPFRINKTDTKPVQMMNLEATFC-LGNIDDINCKIIELPFQNKHLSMLIVLPKDVED 238

  Fly   278 VSLVLKQL-KNLGLHRLLEELEAS-KNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNE-FAD 339
            .|..|::: |.|....||:....| ...:.|::.||||....::..:.::...||..|.|| .:|
  Rat   239 ESTGLEKIEKQLNPETLLQWTNPSTMANAKVKLSLPKFKVEKMIDPKASLESLGLKSLFNESTSD 303

  Fly   340 LGRMLIPTGDRGAYLS-LYHQFARIVVDEEGLPNAVPQKSSGTNNIKFHINRPFAYLVLQRTHKL 403
            ...|   :..:|..:| :.|:....:.::.|....||......:..:|..:.||.::|.....:.
  Rat   304 FSGM---SETKGVSVSNVIHRVCLEITEDGGDSIEVPGSRILQHKDEFKADHPFLFIVRHNKTRN 365

  Fly   404 LIHSGVF 410
            ::..|.|
  Rat   366 IVFLGKF 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	88/395 (22%)
Serpinb5	NP_476449.2	serpinB5_maspin	1..375	CDD:381013	89/397 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110