DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Bc and Serpini1

DIOPT Version :9

Sequence 1:	NP_001262103.1	Gene:	Spn77Bc / 40236	FlyBaseID:	FBgn0036970	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_446231.1	Gene:	Serpini1 / 116459	RGDID:	619896	Length:	410	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	103/434 - (23%)
Similarity:	188/434 - (43%)	Gaps:	70/434 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LGFLGLFGMVLSLRAHICANTVDTKSLLQKMTDARLQFALNLLQMESTHLNL----ENFAMTPFS 63
            :.:|||..:| :|::.:.......:::        .::::|:.    .||..    ||...:|.|
  Rat     1 MAYLGLLSLV-ALQSLVTGAAFPDETI--------AEWSVNVY----NHLRATGEDENILFSPLS 52

  Fly    64 TWSLMIMFYEGAEGTTLKQIR-----DVLAIYVDYPTLRRWYEDVRAY--HYLNSENTKLFSLRY 121
            ....|.:...||:|:|||:||     :.|....::..||.:...|.|.  .|:......|| ::.
  Rat    53 IALAMGVMELGAQGSTLKEIRHSMGYESLKSGEEFSFLRDFSSMVSAEEGQYVMKIANSLF-VQN 116

  Fly   122 AYYDDVGDLELVKGY-NSVVLEGVGEGNVVLREGRPRGVDFDQGASI--IINDDIDKASHAKIFS 183
            .::.:...|:::|.| |:.|                ..|||.:..::  .||..::..:::.:..
  Rat   117 GFHINEEFLQMMKMYFNAEV----------------NHVDFSENVAVANYINKWVENYTNSLLKD 165

  Fly   184 SYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNAGGSPAGKVEMMVQTGKYAY---- 244
            ..|...|::...:..|...|||..||..|....|:...|.....|.. ::.||.|.|::.|
  Rat   166 LVSPGDFDAVTHLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEV-QIPMMYQQGEFYYGEFS 229

  Fly   245 --VNNVKGLQADVLELPFGEHELVMIVILPKPSQRVSLVLKQLKNLGLHRLLEELEASKNESDVE 307
              .|...|:. .|||:|:...|:.|:::|    .|..:.|..|:.|...:|:||...|..:..||
  Rat   230 DGSNEAGGIY-QVLEIPYEGDEISMMLVL----SRQEVPLATLEPLLKPQLIEEWANSVKKQKVE 289

  Fly   308 VKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPN 372
            |.||:|.....:.|:|.:...|:|::..:.|:|..|   :..:..:||.....:.|.|:|||...
  Rat   290 VYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAM---SDKKELFLSKAVHKSFIEVNEEGSEA 351

  Fly   373 AVPQKSSGTNNI--------KFHINRPFAYLVLQRTHKLLIHSG 408
            ||   :||...|        :..::.||.:|:..|....::..|
  Rat   352 AV---ASGMIAISRMAVLFPQVIVDHPFLFLIKNRKTGTILFMG 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_001262103.1	SERPIN	36..410	CDD:238101	98/401 (24%)
Serpini1	NP_446231.1	neuroserpin	23..410	CDD:239003	98/411 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920