Protein Alignment Spn77Bc and Serpina3a

DIOPT Version :10

• Sequence 1: NP_649207.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: XP_006240581.2
• Gene: Serpina3a / 100909605
• RGDID: 6502633
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 100/403 - (24%)
• Similarity: 170/403 - (42%)
• Gaps: 47/403 - (11%)

  Fly    24 VDTKSLLQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLA 88
            ||:.:|....||    ||.:|.:........:|...:.||..:.:::...||:..|||:|.:.|.
  Rat    32 VDSSTLSSCNTD----FAFSLYKELVLKNPDKNIVFSSFSISTALVLLSLGAKNNTLKEILEGLK 92

  Fly    89 I-YVDYP--TLRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVV 150
            . ..:.|  .:.:.||.:.....|..:..::         ..|....:|.:..::.| ..|....
  Rat    93 FNLTETPEAEIHQGYEHLLQRLNLPGDQVQI---------STGSALFIKKHLQILAE-FQEKARA 147

  Fly   151 LREGRPRGVDFDQ--GASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFD 213
            |.:......||.|  .|..:|||.:.|.:..||....|  ..:...:::.:...|||.|||.|||
  Rat   148 LYQAEAFSTDFQQPHEAKKLINDYVRKQTQGKIKELIS--VLDKKTSMVLVNYIYFKGKWKMPFD 210

  Fly   214 KSQTKVEQFYNAGGSPAGKVEMM-VQTGKYAYVNNVKGLQADVLELPFGEHELVMIVILPKPSQ- 276
            ...|...:|| .....:.||.|| ::.....|..: :.|...||||.:..:...:.::   |.|
  Rat   211 PHDTFQSEFY-LDEKKSVKVPMMKIEKLTTPYFRD-EELSCSVLELKYTGNASALFIL---PDQG 270

  Fly   277 RVSLVLKQLKNLGLHRLLEELEASKNESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEFADLG 341
            |:..|...|:...|.|..:.|...:.:   |:::|||...:.:.|.|.:.|.|:.::.::.|||.
  Rat   271 RMQQVEASLQPETLRRWKDTLRPRRID---ELRMPKFSISTDMRLGDILPELGIREVFSQQADLS 332

  Fly   342 RMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQKSSGTNNI----KF-----HINRPFAYLVL 397
            |:   ||.:...:|.....|.:.|.|.|...|.   ::|...|    ||     :.||||..::.
  Rat   333 RI---TGAKDLSVSQVVHKAVLDVTETGTEAAA---ATGVKIIPMCAKFYYVTMYFNRPFLMIIS 391

  Fly   398 Q-RTHKLLIHSGV 409
            . .||..|..:.|
  Rat   392 DTNTHIALFMAKV 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bc	NP_649207.1	serpin	33..412	CDD:476815	97/394 (25%)
Serpina3a	XP_006240581.2	serpinA3_A1AC	27..408	CDD:381019	100/403 (25%)