Protein Alignment Spn77Bb and SERPINE3

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 84/360 - (23%)
• Similarity: 141/360 - (39%)
• Gaps: 78/360 - (21%)

  Fly    20 GAEGYTVNELRDVLGIYVDYPTLRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGD------LEL 78
            ||||.|..:|.|.||..|....::.:...|.|....:|:.|:: .|..:.:..||.      :|.
Human    67 GAEGSTGQQLADALGYTVHDKRVKDFLHAVYATLPTSSQGTEM-ELACSLFVQVGTPLSPCFVEH 130

  Fly    79 VKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKASHA-----------KIFSSYS 132
            |..:.:..||...     |.|.....:...:|||      .:.|...           ::.::::
Human   131 VSWWANSSLEPAD-----LSEPNSTAIQTSEGAS------RETAGGGPSEGPGGWPWEQVSAAFA 184

  Fly   133 RRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNDGGSPAGKVEMMVQTGK--YAYVNNVK 195
            :....||::        |:..|:..|..:.|::..|....|... :|.||.||.:  |....:..
Human   185 QLVLVSTMS--------FQGTWRKRFSSTDTQILPFTCAYGLVL-QVPMMHQTTEVNYGQFQDTA 240

  Fly   196 GLQADVLELPFGEHELVMIVLLPKSSQGVNLVLYQLKNLGLHRLLEKLEASK--------NETDV 252
            |.|..|||||:....:.:.::||:.           |:..|..:...|.||.        ....:
Human   241 GHQVGVLELPYLGSAVSLFLVLPRD-----------KDTPLSHIEPHLTASTIHLWTTSLRRARM 294

  Fly   253 EVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAI-GHRGACLTLYHQFARIVVDEEGL 316
            :|.||:|..::..:|:..:...|:|||   |..|...|..| |..|..::.....|:|.|.|||
Human   295 DVFLPRFRIQNQFNLKSILNSWGVTDL---FDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEG- 355

  Fly   317 PNAVPQKSSGKNNIK---------FHVNRPFAYLV 342
                 .|:||...:.         |..:|||.|.:
Human   356 -----TKASGATALLLLKRSRIPIFKADRPFIYFL 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	84/360 (23%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	84/360 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		6/41 (15%)