Protein Alignment Spn77Bb and SERPINF2

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 89/362 - (24%)
• Similarity: 143/362 - (39%)
• Gaps: 74/362 - (20%)

  Fly    20 GAEGYTVNELRDVL--GIYVDYP-TLRRWYED-------VRAYHYLNSENTKLFSLRYAYYDDVG 74
            ||:.:|:..|:.||  |.....| .|.|..:|       :.|..||.    |.|.::   .|.:.
Human   139 GAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQ----KGFPIK---EDFLE 196

  Fly    75 DLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNS- 138
            ..|.:.|...|.|.|..|.::.                 .||..:.:|:..||      :.|.|
Human   197 QSEQLFGAKPVSLTGKQEDDLA-----------------NINQWVKEATEGKI------QEFLSG 238

  Fly   139 ----TVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNDGGSPAGKVEMMVQTGKYA---YVNNVKG 196
                ||.:| :...:|:..|:..||.|.|:.:.|:.|..... .|||| |...|.   ::.....
Human   239 LPEDTVLLL-LNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTV-PVEMM-QARTYPLRWFLLEQPE 300

  Fly   197 LQADVLELPFGEHELVMIVLLPKSSQ-GVNLVLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFD 260
            :|  |...|| ::.:..:||:|...: .|:.||..|....||..|..      |...:|:|||..
Human   301 IQ--VAHFPF-KNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVW------ERPTKVRLPKLY 356

  Fly   261 TRSVLSLEDTVYDAGLTDL--RNDFADL-DKLLIAIGHRGACLTLYHQFARIVVDEEGLPNAVPQ 322
            .:..:.|..|:...||.:|  ..|...: ::.|:..|       :.|| :.:.:.|.|:..|...
Human   357 LKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSG-------VQHQ-STLELSEVGVEAAAAT 413

  Fly   323 K--SSGKNNIKFHVNRPFAYLVLQKKHKLLIHSGVFR 357
            .  .|..:...|.|||||.:.:.:....|.:..|..|
Human   414 SIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVR 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	89/362 (25%)
SERPINF2	XP_005256758.2	serpinF2_A2AP	91..454	CDD:381009	89/362 (25%)