Protein Alignment Spn77Bb and SERPINA4

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 78/327 - (23%)
• Similarity: 127/327 - (38%)
• Gaps: 73/327 - (22%)

  Fly    42 LRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVD 106
            |.::..|..|.:     ..|||...  :||.||.::|
Human   189 LAKFLNDTMAVY-----EAKLFHTN--FYDTVGTIQL---------------------------- 218

  Fly   107 FDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYND 171
                    |||.:.|.:..||....|  .....|.::.:...||||.|:.||..|:|..:.||.|
Human   219 --------INDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVD 273

  Fly   172 GGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQG----VNLVLYQLK 232
            ..:.. :|.||:|..::.:..:.:.|...||.:.: :.:..:..:||  :||    :..||....
Human   274 ENTTV-RVPMMLQDQEHHWYLHDRYLPCSVLRMDY-KGDATVFFILP--NQGKMREIEEVLTPEM 334

  Fly   233 NLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHRG 297
            .:..:.||.|....|.   :|:.||||.......|:..:...|.|||.:.:|||..  |....:.
Human   335 LMRWNNLLRKRNFYKK---LELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG--ITKQQKL 394

  Fly   298 ACLTLYHQFARIVVDEEGLPNAVPQKSSGKNNIKF-------HV---NRPFAYLVLQKKHKLLIH 352
            .....:|: |.:.|||.|...|.....:    |||       |:   ||||..::.....:.::.
Human   395 EASKSFHK-ATLDVDEAGTEAAAATSFA----IKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLF 454

  Fly   353 SG 354
            .|
Human   455 LG 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	78/327 (24%)
SERPINA4	NP_001275961.1	serpinA4_KST	81..463	CDD:381020	78/327 (24%)