Protein Alignment Spn77Bb and SERPINF1

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_002606.3
• Gene: SERPINF1 / 5176
• HGNCID: 8824
• Length: 418
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 58/263 - (22%)
• Similarity: 107/263 - (40%)
• Gaps: 55/263 - (20%)

  Fly   100 GRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTK 164
            |.|| :|..:     ||:.:......|:  :.|.:.....:::|.:.|::||.:|...||..:|.
Human   171 GNPR-LDLQE-----INNWVQAQMKGKL--ARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTS 227

  Fly   165 VEQFYNDGGSPAGKVEMMVQTG---KYAYVNNVKGLQAD----VLELPFGEHELVMIVLLPKSSQ 222
            :|.||.|..... :|.||....   :|       ||.:|    :.:||......::..|..|.:|
Human   228 LEDFYLDEERTV-RVPMMSDPKAVLRY-------GLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQ 284

  Fly   223 GVNLVLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLR----NDF 283
            .:.|:...|.:..:|.:..:|:.    ....:.:||..    ||.|..| ...|.:::    .|.
Human   285 NLTLIEESLTSEFIHDIDRELKT----VQAVLTVPKLK----LSYEGEV-TKSLQEMKLQSLFDS 340

  Fly   284 ADLDKL------LIAIGHRGACLTLYHQFARIVVDEEG---LPNAVPQKSSGKNNIKFHVNRPFA 339
            .|..|:      |..:.||          |....:|:|   .|:...|.:.....:.:|:|:||.
Human   341 PDFSKITGKPIKLTQVEHR----------AGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFI 395

  Fly   340 YLV 342
            :::
Human   396 FVL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	58/263 (22%)
SERPINF1	NP_002606.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39
		serpinF1_PEDF	41..413	CDD:381008	58/263 (22%)
		O-glycosylated at one site	371..383		2/11 (18%)