Protein Alignment Spn77Bb and SERPINA5

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 58/240 - (24%)
• Similarity: 106/240 - (44%)
• Gaps: 19/240 - (7%)

  Fly   110 GASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYNDGGS 174
            ||...|||.:.|.:..||....  ::.:|...|:.:...:|||||:..|:...|:.:.||....:
Human   167 GAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET 229

  Fly   175 PAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQGVNLVLYQLKNLGLHRL 239
            .. :|.||.:..:|.|:.: :.|...|:.:|:..:...:.:|   .|:|   .:.|::|....:.
Human   230 VV-RVPMMSREDQYHYLLD-RNLSCRVVGVPYQGNATALFIL---PSEG---KMQQVENGLSEKT 286

  Fly   240 LEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHRGACLTLYH 304
            |.|......:..:|:.||||.......||..:...|::::....|||..:   ..|....::...
Human   287 LRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGI---SNHSNIQVSEMV 348

  Fly   305 QFARIVVDEEGLPNAVPQ------KSSGKNNIKFHVNRPFAYLVL 343
            ..|.:.|||.|...|...      :|:..|:.:...||||...::
Human   349 HKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	58/240 (24%)
SERPINA5	NP_000615.3	serpinA5_PCI	44..406	CDD:381021	58/240 (24%)