Protein Alignment Spn77Bb and Serpinh1

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_058869.2
• Gene: Serpinh1 / 29345
• RGDID: 69302
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 71/312 - (22%)
• Similarity: 117/312 - (37%)
• Gaps: 63/312 - (20%)

  Fly    89 GVGEGNVVLREGRPRGVDFDQG------ASIIINDDIDKAS-------HAKIFSSYSRRSFNS-- 138
            |:||....|.....|.|.:..|      :|:...||..::|       |:||.....|.:..|
  Rat   109 GLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSIN 173

  Fly   139 --------------------TVTVLGITVSYFKAKWKYPF-----DKSQTKVEQFYNDGGSPAGK 178
                                |...|.:...:||..|...|     |.....|.:.|..|
  Rat   174 EWASQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVG------ 232

  Fly   179 VEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQGVNLVLYQLKNLGLHRLLEKL 243
            |.||.:||.|.|.::.|. :..::|:|.......:|:|:|...:    .|.:|:.|.....|:..
  Rat   233 VTMMHRTGLYNYYDDEKE-KLQLVEMPLAHKLSSLIILMPHHVE----PLERLEKLLTKEQLKTW 292

  Fly   244 EASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTD-LRNDFADLDKLLIAIGHRGACL-TLYHQF 306
            .....:..|.:.|||........|:..:...|||: :..:.|||.::   .|.:...| :::|..
  Rat   293 MGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRM---SGKKDLYLASVFHAT 354

  Fly   307 ARIVVDEEGLPNAVPQKSSGKNNIK----FHVNRPFAYLVLQKKHKLLIHSG 354
            | ...|.||  |...|...|:..::    |:.:.||.:||...:...|:..|
  Rat   355 A-FEWDTEG--NPFDQDIYGREELRSPKLFYADHPFIFLVRDNQSGSLLFIG 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	71/312 (23%)
Serpinh1	NP_058869.2	serpinH1_CBP1	35..416	CDD:381003	71/312 (23%)
		Prevents secretion from ER. /evidence=ECO:0000305	414..417