Protein Alignment Spn77Bb and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 384
• Identity: 85/384 - (22%)
• Similarity: 142/384 - (36%)
• Gaps: 112/384 - (29%)

  Fly    14 MIMFYEGAEGYTVNELRDVLGIYVDYPTLRRWYEDVRA-YHYLNSENTKL-----FSLRYAYYDD 72
            :.|.:.||:|.|..:|...|  :.|.      .||:.: :..|.:|.:||     ..|....|.:
Mouse    39 LAMVFLGAKGSTAAQLSKTL--HFDS------VEDIHSCFQSLTAEVSKLGASHTLKLANRLYGE 95

  Fly    73 VGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDF---DQGASIIINDDIDKASHAKIFSSYSRR 134
                   |.||  .|.........:.......|||   .:.|...||..:...:..||....::.
Mouse    96 -------KTYN--FLPEFLASTQKMYSADLAAVDFQHASEDARKEINQWVKGQTEGKIPELLAKG 151

  Fly   135 SFNSTVTVLGITVSYFKAKWKYPF------------DKSQTKVEQFYNDGGSPAGKVEMMVQTGK 187
            ..:|...::.:...|||..|:..|            :|..||.             |:||.|..|
Mouse   152 VVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKT-------------VKMMYQKKK 203

  Fly   188 YAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQGVNLVLYQLKNLGLHRLLEKL------EAS 246
            :.: ..:..|:..|||:|:...||.|::|||:..:.        ::.||.::.|:|      |.:
Mouse   204 FPF-GYISDLKCKVLEMPYQGGELSMVILLPEDIED--------ESTGLKKIEEQLTLGKLHEWT 259

  Fly   247 KNET----DVEVKLPKFDTRS---------VLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHRGA 298
            |:|.    ||.||||:|....         .|.::| ::.:|..||.......|..:..|.|:
Mouse   260 KHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQD-LFSSGKADLSGMSGSRDLFVSKIVHK-- 321

  Fly   299 CLTLYHQFARIVVDEEGLPNA---------------VPQKSSGKNNIKFHVNRPFAYLV 342
                    :.:.|:|:|...|               .||:       .|.|:.||.:.:
Mouse   322 --------SFVDVNEQGTEAAAATGGIIQVLCEKMPTPQE-------VFTVDHPFLFFI 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	85/384 (22%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	85/384 (22%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		5/21 (24%)