Protein Alignment Spn77Bb and Serpina1b

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_033270.3
• Gene: Serpina1b / 20701
• MGIID: 891970
• Length: 413
• Species: Mus musculus
• Alignment Length: 324
• Identity: 71/324 - (21%)
• Similarity: 131/324 - (40%)
• Gaps: 74/324 - (22%)

  Fly    34 GIYV--DYPTLRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVV 96
            |::|  |...:.::.|:.: .||    ..::||:.:|..::
Mouse   135 GLFVNNDLKLVEKFLEEAK-NHY----QAEVFSVNFAESEE------------------------ 170

  Fly    97 LREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKS 161
                          |..:|||.::|.:..||..:..... ..||..|...: .||.|||.|||..
Mouse   171 --------------AKKVINDFVEKGTQGKIVEAVKELD-QDTVFALANYI-LFKGKWKKPFDPE 219

  Fly   162 QTKVEQFYNDGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQGVNL 226
            .|:..:|:.| .|...||.||:.:|... |::...|.:.||.:.:..:... :.|||:..:
Mouse   220 NTEEAEFHVD-KSTTVKVPMMMLSGMLD-VHHCSILSSWVLLMDYAGNASA-VFLLPEDGK---- 277

  Fly   227 VLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLI 291
             :..|:......|:.|:..::....|::.:|:.......:|:..:...|:|.:.|:.|||.
Mouse   278 -MQHLEQTLNKELISKILLNRRRRLVQIHIPRLSISGDYNLKTLMSPLGITRIFNNGADLS---- 337

  Fly   292 AIGHRGACLTL---YHQFARIVVDEEGLP-------NAVPQKSSGKNNIKFHVNRPFAYLVLQK 345
            .|....|.|.|   .|: |.:.:||.|..       .|||.  |....::|  :.||.:::.::
Mouse   338 GITEENAPLKLSKAVHK-AVLTIDETGTEAAAATVFEAVPM--SMPPILRF--DHPFLFIIFEE 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	71/324 (22%)
Serpina1b	NP_033270.3	serpinA1_A1AT	44..412	CDD:381012	71/324 (22%)
		RCL	368..387		5/22 (23%)