Protein Alignment Spn77Bb and Serpina1a

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 328
• Identity: 68/328 - (20%)
• Similarity: 129/328 - (39%)
• Gaps: 82/328 - (25%)

  Fly    34 GIYV--DYPTLRRWYEDVRAYHYLNSENTKLFSLRYAYYDDVGDLELVKGYNSVVLEGVGEGNVV 96
            |::|  |...:.::.|:.: .||    ..::||:.:|..::
Mouse   158 GLFVNNDLKLVEKFLEEAK-NHY----QAEVFSVNFAESEE------------------------ 193

  Fly    97 LREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKS 161
                          |..:|||.::|.:..||..:..:.. ..||..|...: .||.|||.|||..
Mouse   194 --------------AKKVINDFVEKGTQGKIAEAVKKLD-QDTVFALANYI-LFKGKWKKPFDPE 242

  Fly   162 QTKVEQFYNDGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIVLLPKSSQGVNL 226
            .|:..:|:.| .|...||.||..:| ..:|::...|.:.||.:.:..: ...:.|||...:
Mouse   243 NTEEAEFHVD-ESTTVKVPMMTLSG-MLHVHHCSTLSSWVLLMDYAGN-ATAVFLLPDDGK---- 300

  Fly   227 VLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLI 291
             :..|:......|:.|...::.....::..|:.......:|:..:...|:|.:.|:.|||.
Mouse   301 -MQHLEQTLSKELISKFLLNRRRRLAQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLS---- 360

  Fly   292 AIGHRGACLTL---YHQFARIVVDEEG-----------LPNAVPQKSSGKNNIKFHVNRPFAYLV 342
            .|....|.|.|   .|: |.:.:||.|           :|.::|.      .::|  :.||.:::
Mouse   361 GITEENAPLKLSQAVHK-AVLTIDETGTEAAAVTVLQMVPMSMPP------ILRF--DHPFLFII 416

  Fly   343 LQK 345
            .::
Mouse   417 FEE 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	68/328 (21%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	68/328 (21%)