Protein Alignment Spn77Bb and AGT

DIOPT Version :10

• Sequence 1: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001369746.2
• Gene: AGT / 183
• HGNCID: 333
• Length: 476
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 84/398 - (21%)
• Similarity: 152/398 - (38%)
• Gaps: 97/398 - (24%)

  Fly     1 MKLGFLG---------LFGMV-------------LMIMFYEGAEGYTVNELRDVLGI-YVDYPTL 42
            |...|||         |:|:|             .:...|.||..:|.:.|:.:||: :.|....
Human    99 MLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCT 163

  Fly    43 RRWYEDVRAYHYL----------------NSENTKLFSLRYAYYDDVGDLEL----VKG---YNS 84
            .|    :.|:..|                :|:...|.|.....:...| |.|    |:|   |..
Human   164 SR----LDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPG-LHLKQPFVQGLALYTP 223

  Fly    85 VVLEGVGEGNVVLREGRPRGVDFDQGASIIINDDIDKASHA----KIFSSYSRRSFNSTVTVLGI 145
            |||              ||.:||.:  ..:..:.||:...|    |...|....|.:||:..  .
Human   224 VVL--------------PRSLDFTE--LDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAF--N 270

  Fly   146 TVSYFKAKWKYPFDKSQTKVEQFYNDGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHE 210
            |..:|:.|.| .| ....:.::|:.| .|.:..|.|:...|.:.:.::::. ...|.::||.| .
Human   271 TYVHFQGKMK-GF-SLLAEPQEFWVD-NSTSVSVPMLSGMGTFQHWSDIQD-NFSVTQVPFTE-S 330

  Fly   211 LVMIVLLPKSSQGVNLV---LYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVY 272
            ..::::.|..:..::.|   .:|..:|   ..::||    :...:.:.:|:...:....|:|.:.
Human   331 ACLLLIQPHYASDLDKVEGLTFQQNSL---NWMKKL----SPRTIHLTMPQLVLQGSYDLQDLLA 388

  Fly   273 DAGLTDLRNDFADLDKL---LIAIGHRGACLTLYHQFARIVVDEEGLPNAVPQKSSGKNNIKFHV 334
            .|.|..:.:...:|.||   .|.:|.     .|...|..:..||.. |....|:.:....::..:
Human   389 QAELPAILHTELNLQKLSNDRIRVGE-----VLNSIFFELEADERE-PTESTQQLNKPEVLEVTL 447

  Fly   335 NRPFAYLV 342
            ||||.:.|
Human   448 NRPFLFAV 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Bb	NP_649206.1	serpin	13..358	CDD:476815	77/364 (21%)
AGT	NP_001369746.2	serpinA8_AGT	28..474	CDD:381010	84/398 (21%)