Protein Alignment Spn77Ba and SERPINB11

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001357404.1
• Gene: SERPINB11 / 89778
• HGNCID: 14221
• Length: 392
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 117/419 - (27%)
• Similarity: 186/419 - (44%)
• Gaps: 71/419 - (16%)

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDE 135
            |:|....:|.||:.:.::  ......:...|..|:...|.::..|:.|||..||:|.|..:...:
Human     3 SLSTANVEFCLDVFKELN--SNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVD 65

  Fly   136 KLRGAYK----------VWSSF------LNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQN-YN 183
            .|:..:|          :.|.|      :|...|...::....:|..|.......|....:. |.
Human    66 SLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWYQ 130

  Fly   184 VQPMEVDFYSPDSVIQINEDTNRT--------TRGLI-----PYTILPQDVYGAKMFLLSSLYFK 235
            .:...|||.      |..|:|.:|        |.|.:     ..||.|..|    |.|::::|||
Human   131 ARLQTVDFE------QSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSV----MVLVNAIYFK 185

  Fly   236 GQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANF--AYVSNVEGLDGYVLELPYGTQDRLAM 298
            |||:..|....|.:.||....|:.: .:.||.|...|  |:|...:   ..|||||| ..::|:|
Human   186 GQWQNKFQVRETVKSPFQLSEGKNV-TVEMMYQIGTFKLAFVKEPQ---MQVLELPY-VNNKLSM 245

  Fly   299 IVVLPKRGFKLNDVANNLKALGLRPILQRL--AAFRNRASEDN----EVEVMMPKFVTATDFTLK 357
            |::||.      .:||      |:.|.::|  ..|....|..|    ||||.:|:|...|.:.|.
Human   246 IILLPV------GIAN------LKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELN 298

  Fly   358 GVLIQMGIRDLFDENTANLDRMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATP--P 418
            .:|..:|:.|||::..|:|..||  .||:....:|.:.:.|.|:||.|.|.|..::|.|:.|  .
Human   299 SLLKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRA 363

  Fly   419 KFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            :|..|.||.:.|....|..:||.|::.:|
Human   364 QFKANHPFLFFIRHTHTNTILFCGKLASP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	114/410 (28%)
SERPINB11	NP_001357404.1	ovalbumin_like	4..392	CDD:239014	115/416 (28%)
		RCL. /evidence=ECO:0000250	341..365		9/23 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030