Protein Alignment Spn77Ba and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 112/442 - (25%)
• Similarity: 194/442 - (43%)
• Gaps: 71/442 - (16%)

  Fly    63 NFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKS 127
            :|..|.||:.:   ..|..||.|.|.  .:..:|:...||.|:.:.|.::..|:..::.:|:.:.
Human    10 SFTMDSLVTAN---TKFCFDLFQEIG--KDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEV 69

  Fly   128 LRIN---------------------VEDEKLRGAYK-------------------------VWSS 146
            |..|                     :.|..|.|..|                         :.|.
Human    70 LHFNEFSQNESKEPDPCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSK 134

  Fly   147 FLNITTS-TIEVATLQAIYTGKGYPIKNNYRD-AIQNYNVQPMEVDFY-SPD-SVIQINEDTNRT 207
            ...|.|. |:.:|  ..:|..:.:||...|.| .||.|:.....|||. :|: |..:||......
Human   135 LDRIKTDYTLSIA--NRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQ 197

  Fly   208 TRGLIPYTILPQDVYGAK--MFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEA 270
            ::|.|. .:..:|...|:  :.|::::|||.:|:..|:...|.:.||...:.| ...:.||.|:.
Human   198 SQGKIK-ELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANE-NKSVKMMTQKG 260

  Fly   271 NFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRA 335
            .:. :..:|.:...:||:.| |:.:|:|.|:||...   .|....|:.|..:...:::.|:.:..
Human   261 LYR-IGFIEEVKAQILEMRY-TKGKLSMFVLLPSHS---KDNLKGLEELERKITYEKMVAWSSSE 320

  Fly   336 SEDNE-VEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRM--SSGLFAKLVVHSTKIIVD 397
            :...| |.:..|:|.....:.|..:|..|||.|:|||..|:|..:  |..|:...::|.|.:.||
Human   321 NMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVD 385

  Fly   398 EQGTTAGAVTEAALANKATPP--KFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |.||.|.|.|.|.::.::...  :|..|.||.:.|....|..:||.|:|.:|
Human   386 ENGTQAAAATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	106/425 (25%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	109/434 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030