DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and zgc:173729

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001103200.1	Gene:	zgc:173729 / 798311	ZFINID:	ZDB-GENE-071004-64	Length:	439	Species:	Danio rerio

Alignment Length:	446	Identity:	113/446 - (25%)
Similarity:	196/446 - (43%)	Gaps:	78/446 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRIN---- 131
            |:|.....|:|:|.::||  ...|:.:...||.|:.|.|.::..|::|.|.:|:.|.|..|
Zfish     3 SLSAANTQFSLNLFKKIS--GGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNPPK 65

  Fly   132 -----------------------------------------------------VEDEKLRGAYKV 143
                                                                 ..:|::..::..
Zfish    66 PGGATPTPAQATQKPQITCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFNK 130

  Fly   144 WSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPME-VDF--YSPDSVIQINEDTN 205
            :.|.||...:...::....:|..:.|.....:....:.|....:| |||  .|..|.:.||:...
Zfish   131 FMSELNKPGAPYVLSLANRLYGEQTYQFLEKFLSDAKTYYAAGLEKVDFKNKSEASRVNINKWVE 195

  Fly   206 RTTRGLIPYTILPQDVYGA--KMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQ 268
            :.|:..|. .:||.....|  ::.|::::||||.|:..|.|..||:..|.....:. ..:.||.|
Zfish   196 KNTQEKIK-DLLPSGAIDAMTRLVLVNAIYFKGNWEKKFTKEATRDGQFKLNKNQT-KPVKMMHQ 258

  Fly   269 EANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRN 333
            :|.|: ::::..::..||||||..:: |:|:::||.   ::.|....|:.|......::|..:..
Zfish   259 KARFS-LASIPEMNSQVLELPYAGKN-LSMLIILPD---QIEDATTGLQKLEKALTYEKLMEWTK 318

  Fly   334 RASE-DNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSG--LFAKLVVHSTKII 395
            .:.. ..||:|.:|||.|...:.:|.:|:.||:.|:||....||..|||.  |....|:|...:.
Zfish   319 PSMMCQQEVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLVLSKVIHKAFVE 383

  Fly   396 VDEQGTTAGAVTE--AALAN-KATPPK-FLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |:|:||.|.|.|.  |.|.: ..:||| |..:.||.:.|....|..:||.|:..:|
Zfish   384 VNEEGTEAAAATGVIATLTSMPLSPPKTFTADHPFIFFIRHNPTNAILFYGRFSSP 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	110/437 (25%)
zgc:173729	NP_001103200.1	SERPIN	4..439	CDD:294093	111/443 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030