DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and zgc:174259

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_021331992.1	Gene:	zgc:174259 / 791587	ZFINID:	ZDB-GENE-080213-10	Length:	410	Species:	Danio rerio

Alignment Length:	453	Identity:	125/453 - (27%)
Similarity:	190/453 - (41%)	Gaps:	65/453 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LMLWIPLLLG-AIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVS 71
            :.|||   .| ||.:|     .||..||..   |::|                        .|.|
Zfish     6 VFLWI---CGFAIVVC-----GNQETLQQP---PISA------------------------KLPS 35

  Fly    72 ISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEK 136
            :.....|||..|.:|:....:..:|:...|||||...|..|..|:.|:|:.||...:..:.....
Zfish    36 LINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSGIGYSSAIFS 100

  Fly   137 LRGAYKVWSSFL----NITTSTIEVATLQAIYTGKGY-PIKNNYRDAIQNYNVQPMEVDFYSPDS 196
            ....::::.|.|    |.|...|:|.|  |:|....: |......|..:.|:.....|||...::
Zfish   101 TEEMHQLFHSLLEDIGNRTGVDIDVGT--ALYASDRFKPHSKFLEDMKEFYHSDGFTVDFSVKET 163

  Fly   197 VIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            |.|||:.....|.|.|...:  |..|.:   |.||:.:||||:|..|||...|.|..|..:....
Zfish   164 VDQINKYVEEKTHGKINQAVDDLDADTF---MVLLTYIYFKGKWDKPFNPKTTSESTFHIDDKTT 225

  Fly   260 IGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDV---ANNLKALGL 321
            : .:.||.|........:.| |...||.|.|  .|..:|.:.:|       ||   ...:|.|.:
Zfish   226 V-PVQMMHQYERLKVYYDAE-LSTKVLCLDY--NDSFSMFLAVP-------DVHMGRKTIKDLEM 279

  Fly   322 RPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAK 386
            ....|.:..:|...|| .:|::.:||....|.::||.:|..||:.|:|.:...........::..
Zfish   280 TVSRQHVEKWRRSVSE-RKVDIYVPKLSLKTSYSLKDILKGMGMADMFSDKADFTGVSEEKIYVS 343

  Fly   387 LVVHSTKIIVDEQGTTAGAVTEAALANKATPP--KFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            .|:|...:.:||:||||.|||...|...:..|  ....:|||...|.::....:||.|:|.||
Zfish   344 KVLHKATLDIDEKGTTAAAVTTVHLRFMSYSPMSDLSFDRPFMIFITDQTNDNILFVGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	107/380 (28%)
zgc:174259	XP_021331992.1	alpha-1-antitrypsin_like	39..403	CDD:239011	107/380 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910