DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn77Ba and Serpina9

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001348839.1	Gene:	Serpina9 / 71907	MGIID:	1919157	Length:	418	Species:	Mus musculus

Alignment Length:	426	Identity:	112/426 - (26%)
Similarity:	198/426 - (46%)	Gaps:	39/426 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LTAFTAP-------TAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDF 98
            |..|.||       ..:....||:.||:.|..:.|..|.::    |:..|.||::  .|...::.
Mouse    12 LVGFCAPIFCMLSSNPYNQESSHLPSMKKNPASQVSPSNTR----FSFLLYQRLA--QENPGQNI 70

  Fly    99 MISPFSVWSLLVLLYEGSEGETRNQLKKSLRIN---VEDEKLRGAYKVWSSFLNITTSTIEVATL 160
            :.||.|:.:.|.:|..|:...|:.|:.::|..|   |.:..:...::.....||......|:...
Mouse    71 LFSPVSISTSLAMLSLGARSATKTQILRTLGFNFTWVSEPTIHMGFEYLVRSLNKCHQGRELRMG 135

  Fly   161 QAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFYSPDSV-IQINEDTNRTTRGLIPYTILPQDVYG 223
            ..::..|...::..:.|.::. |..:....||.:..:. .|||....:.|:|.:...|...|...
Mouse   136 SVLFIRKELQLQATFLDRVKKLYGAKVFSEDFSNAATAQAQINSYVEKETKGKVVDVIQDLDSQT 200

  Fly   224 AKMFLLSSLYFKGQWKFPFNKTLTREE-PFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLE 287
            | |.|::.::||..|..||:...|.:. ||....|..: .:|||.|..:||:..:.| |...:|:
Mouse   201 A-MVLVNHIFFKANWTQPFSTANTNKSFPFLLSKGTTV-HVPMMHQTESFAFGVDKE-LGCSILQ 262

  Fly   288 LPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTAT 352
            :.| ..|.:|.. |||.:| |:..:..:|.|..||.        .:|:.:...::|.:|||..:.
Mouse   263 MDY-RGDAVAFF-VLPGKG-KMRQLEKSLSARRLRK--------WSRSLQKRWIKVFIPKFSISA 316

  Fly   353 DFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKL--VVHSTKIIVDEQGTTAGAVTEAAL--AN 413
            .:.|:.:|.:|||||.|:.| |:...::...|.::  ..|...:.|.|:||.|.|.|...|  .:
Mouse   317 SYNLETILPKMGIRDAFNSN-ADFSGITKTHFLQVSKAAHKAVLDVSEEGTEAAAATTTKLIVRS 380

  Fly   414 KATPPKFL-LNRPFQYMIVEKATGLLLFAGQVRNPK 448
            :.||...: ...||..::::|.|..:||.|:|.||:
Mouse   381 RDTPSSIIAFKEPFLILLLDKNTESVLFLGKVENPR 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	98/379 (26%)
Serpina9	NP_001348839.1	alpha-1-antitrypsin_like	49..412	CDD:239011	99/383 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010