Protein Alignment Spn77Ba and SERPINE3

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 394
• Identity: 113/394 - (28%)
• Similarity: 185/394 - (46%)
• Gaps: 51/394 - (12%)

  Fly    78 DFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYK 142
            :|||.|.|  ||...:...:|:|||..|...|.:|..|:||.|..||..:|...|.|::::
Human    32 EFALHLYQ--SVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVK---- 90

  Fly   143 VWSSFLNITTSTI-------EVATLQAIYTGKGYPIKNNYRDAIQ---NYNVQPMEVDFYSPDS- 196
               .||:...:|:       |:....:::...|.|:...:.:.:.   |.:::|  .|...|:|
Human    91 ---DFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEP--ADLSEPNST 150

  Fly   197 VIQINEDTNRTTRGLIPYTILPQDVYG----------AKMFLLSSLYFKGQWKFPFNKTLTREEP 251
            .||.:|..:|.|.|..|    .:...|          |::.|:|::.|:|.|:..|:.|.|:..|
Human   151 AIQTSEGASRETAGGGP----SEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQILP 211

  Fly   252 FFSESGEVIGKIPMMVQ--EANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPK-RGFKLNDVA 313
            |....|.|: ::|||.|  |.|:....:..|....|||||| ....:::.:|||: :...|:.:.
Human   212 FTCAYGLVL-QVPMMHQTTEVNYGQFQDTAGHQVGVLELPY-LGSAVSLFLVLPRDKDTPLSHIE 274

  Fly   314 NNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDR 378
            .:|.|..:......|...|        ::|.:|:|.....|.||.:|...|:.||||...|||..
Human   275 PHLTASTIHLWTTSLRRAR--------MDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKANLKG 331

  Fly   379 MS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFA 441
            :|  .|.:....:|..||.|.|:||.|...|...|..::..|.|..:|||.|.:.|..||:.:|.
Human   332 ISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFF 396

  Fly   442 GQVR 445
            .:::
Human   397 DRIQ 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	113/391 (29%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	113/391 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		10/34 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920