DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn77Ba and serpina7

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_021331940.1	Gene:	serpina7 / 564060	ZFINID:	ZDB-GENE-041010-47	Length:	425	Species:	Danio rerio

Alignment Length:	452	Identity:	129/452 - (28%)
Similarity:	194/452 - (42%)	Gaps:	63/452 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LMLWIPLLLG-AIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVS 71
            :.|||   .| ||.:|     .||..||..   |::|                        .|.|
Zfish    21 VFLWI---FGFAIVVC-----GNQETLQQP---PISA------------------------KLPS 50

  Fly    72 ISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEK 136
            :.....|||..|.:|:....:..:|:...|||||...|..|..|:.|:|:.||...:..|.....
Zfish    51 LINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSGIGYNSAIFS 115

  Fly   137 LRGAYKVWSSFL----NITTSTIEVATLQAIYTGKGY-PIKNNYRDAIQNYNVQPMEVDFYSPDS 196
            ....::::.|.|    |.|...|:|.|  |:|....: |......|..:.|:.....|||...::
Zfish   116 TEEMHQLFHSLLEEIGNRTEVDIDVGT--ALYASDRFKPHSKFLEDMKEFYHSDGFTVDFSVKET 178

  Fly   197 VIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            |.|||:.....|.|.|...:  |.:|..   ||||:.:||||:|..||....|.|..|:.:....
Zfish   179 VDQINKYVEEKTHGKISQAVDNLEKDTL---MFLLTYIYFKGKWDKPFKPETTSESTFYIDDKTT 240

  Fly   260 IGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPI 324
            : .:.||.|..:.....:|| |...||.|.|  .|..:||:.:|....|    ...:|.|.:...
Zfish   241 V-PVQMMHQYEHLKVYYDVE-LFTKVLCLDY--NDSFSMILAVPDVYMK----QKTMKDLEMTVS 297

  Fly   325 LQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKLVV 389
            .|.:..:|...|| .:|::.:||....|.::||.:|..||:.|:|.:...........:|...|:
Zfish   298 RQHIEKWRRSVSE-RKVDIYVPKLSLKTSYSLKDILKGMGMTDMFSDKADFTGVSEENIFVSKVL 361

  Fly   390 HSTKIIVDEQGTTAGAVTEAALANKATPP----KFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |...:.:|||||||.|||...:...:..|    ||  :.||...|.::....:||.|:|.||
Zfish   362 HKATLDIDEQGTTAAAVTGVEIRPTSYDPLSDLKF--DHPFMIFITDQTNDNILFVGKVVNP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	111/379 (29%)
serpina7	XP_021331940.1	alpha-1-antitrypsin_like	54..418	CDD:239011	111/379 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910