DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and serpinh1a

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001103844.1	Gene:	serpinh1a / 555328	ZFINID:	ZDB-GENE-080219-21	Length:	403	Species:	Danio rerio

Alignment Length:	393	Identity:	82/393 - (20%)
Similarity:	175/393 - (44%)	Gaps:	29/393 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 TDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSL-R 129
            :.:..:::......|.:|.|.::  .:|..::.:|||..|.|.|.|:..|.:..|.:|:|..| .
Zfish    22 SSIATTLADNSATLAFNLYQNMA--KDKDIENILISPVVVASSLGLVALGGKSNTASQVKTVLSA 84

  Fly   130 INVEDEKLR-GAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNY-RDAIQNYNVQPMEVDFY 192
            .:|:||:|. |..::.:...|.....:........|........::: :.:.::||....:::|.
Zfish    85 ASVKDEQLHSGLSELLTEVSNPKARNVTWKISNRFYGPSSVSFVDDFLKSSKKHYNYDHSKINFR 149

  Fly   193 SPDSVIQ-INEDTNRTTRGLIPYTILPQDVY---GAKMFLLSSLYFKGQWKFPFNKTLTREEPFF 253
            ...|.:: ||:..:::|.|.:|.  :.:||.   ||  .:::::::|..|...|:..:.....|.
Zfish   150 DKRSAVKAINDWASKSTDGKLPE--VTKDVEKTDGA--MIINAMFYKPHWNEQFHHKMVDNRGFL 210

  Fly   254 SESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKA 318
            ......: .:|||.:...:.::.:... ...|||:|. .....::::::|.....|..|...|..
Zfish   211 VHRSFTV-SVPMMHRTGIYGFLDDTTN-KLLVLEMPL-AHKMSSLVLIMPYHVESLERVEKLLTR 272

  Fly   319 LGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMS--S 381
                   |:|..:.: |.|...|.:.:||........|:..|.::|:.:..|:..|:|..:|  .
Zfish   273 -------QQLNTWVS-AMEQKAVAISLPKVSMEVSHNLQKHLAELGLTEAVDKAKADLSNISGKK 329

  Fly   382 GLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPK-FLLNRPFQYMIVEKATGLLLFAGQVR 445
            .|:...|.|::.:..|.:|....  |.....::...|| |..:.||.:::.:..|..:||.|::.
Zfish   330 DLYLSNVFHASAMEWDTEGNPPD--TSIFGTDQLKNPKLFYADHPFVFLVKDNKTNSILFMGRLI 392

  Fly   446 NPK 448
            .||
Zfish   393 RPK 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	80/378 (21%)
serpinh1a	NP_001103844.1	SERPIN	26..391	CDD:294093	80/383 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110