DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpinb9h

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001357856.1	Gene:	Serpinb9h / 544923	MGIID:	3709608	Length:	377	Species:	Mus musculus

Alignment Length:	395	Identity:	107/395 - (27%)
Similarity:	187/395 - (47%)	Gaps:	38/395 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDE 135
            ::||....||:.||:.:.  .:..:|:...||.|:.|.|.::..|::|:|..|:.::|.:| .||
Mouse     3 TLSQANGTFAIHLLKVLC--QDNPSKNVCYSPMSISSALAMVLLGAKGDTAVQICQALHLN-PDE 64

  Fly   136 KLRGAYKVWSSFLNITTSTIEVATL-QAIYTGKGYPIKNNYRDA-IQNYNVQPMEVDF--YSPDS 196
            .:...:::....||...:.....|: ..::......:...:::: ::.|:.:..::.|  .:.:|
Mouse    65 DVHQGFQLLLHNLNKQNNQKYCLTMANRLFVENTCELLPTFKESCLKFYHSEMEQLSFAEAAEES 129

  Fly   197 VIQINEDTNRTTRGLIPYTILPQDVYGA--KMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            ...||...::.|.|.|| .:|.:|...:  ::.|.::|||.|.|...|.|..|:|.||.....|.
Mouse   130 RQHINMWVSKQTNGKIP-DLLSKDSVNSQTRLILANALYFHGTWCKRFEKNRTKEMPFKINKKET 193

  Fly   260 IGKIPMMVQEANF--AYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLR 322
             ..:.||.:|...  |||..::   ..||.:||...| |..:|:||..|..::.|.|||
Mouse   194 -RPVQMMWREDTLFHAYVKEIQ---AQVLVMPYEGID-LNFVVLLPDEGVDISKVENNL------ 247

  Fly   323 PILQRLAA-----FRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSS- 381
             ..::|.|     |.||    .|..|..|||....|:.:..:|..:||.::||.:.|:|..||:
Mouse   248 -TFEKLTAWTKPEFMNR----TEFHVYYPKFQLQEDYDMNSLLQHLGILNVFDGSKADLSGMSTK 307

  Fly   382 -GLFAKLVVHSTKIIVDEQGTTAGAVTEAA---LANKATPPKFLLNRPFQYMIVEKATGLLLFAG 442
             .|.....||...:.|:|:||.|.|.:...   |.:...|..|..:.||.:.|:...|..:||.|
Mouse   308 ENLCLSEFVHKCVVEVNEEGTEAAAASAVEFIFLCSGPDPETFCADHPFLFFIMHSTTNSILFCG 372

  Fly   443 QVRNP 447
            :..:|
Mouse   373 RFSSP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	104/386 (27%)
Serpinb9h	NP_001357856.1	serpinB	7..374	CDD:381072	104/386 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030