Protein Alignment Spn77Ba and SERPINB8

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 104/386 - (26%)
• Similarity: 182/386 - (47%)
• Gaps: 39/386 - (10%)

  Fly    79 FALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKV 143
            ||:.|.:.:..|....|..|  ||.|:.|.|.:::.|::|.|..|:.::|.:..:.:..||...:
Human    11 FAISLFKILGEEDNSRNVFF--SPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGFQSL 73

  Fly   144 WSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPMEVDFYSPDSV---IQINEDTN 205
            .|. :|.|.:...:.|...::..|......::::..|.:....:|...::.|:.   ..||:...
Human    74 LSE-VNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVA 137

  Fly   206 RTTRGLIPY-----TILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPM 265
            ..|.|.|..     |:.|.    .|:.|::::||||:|...|::..||...|  ::.|....:.|
Human   138 EKTEGKISEVLDAGTVDPL----TKLVLVNAIYFKGKWNEQFDRKYTRGMLF--KTNEEKKTVQM 196

  Fly   266 MVQEANF--AYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRL 328
            |.:||.|  .|...|.   ..|||||| .::.|:|:::||...   .|:|...|||    ..::.
Human   197 MFKEAKFKMGYADEVH---TQVLELPY-VEEELSMVILLPDDN---TDLAVVEKAL----TYEKF 250

  Fly   329 AAFRNRASE---DNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKL--V 388
            .|:.|  ||   .::|:|.:|:......:.|:..|.::|:.|.|||..|:...||:.....|  |
Human   251 KAWTN--SEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKV 313

  Fly   389 VHSTKIIVDEQGTTAGAVTEAALANKAT--PPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            .|...:.|:|:||.|.|.|.....::.:  .|:|..:.||.:.|....|..:||.|:..:|
Human   314 AHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	103/381 (27%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	103/384 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030