Protein Alignment Spn77Ba and SERPINA4

DIOPT Version :10

• Sequence 1: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 106/419 - (25%)
• Similarity: 182/419 - (43%)
• Gaps: 49/419 - (11%)

  Fly    52 SGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGS 116
            |..||.|.:.:...:..| .|:....|||......|:.|.  ..|:...||.|:.:...:|..|:
Human    69 SNSSHQQILETGEGSPSL-KIAPANADFAFRFYYLIASET--PGKNIFFSPLSISAAYAMLSLGA 130

  Fly   117 EGETRNQLKKSLRINV----EDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNY-R 176
            ...:|:|:.:.|..|:    |.:..||...:..: ||:....:|.....|::..........: .
Human   131 CSHSRSQILEGLGFNLTELSESDVHRGFQHLLHT-LNLPGHGLETRVGSALFLSHNLKFLAKFLN 194

  Fly   177 DAIQNYNVQPMEVDFYSPDSVIQ-INEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQW 238
            |.:..|..:....:||.....|| ||:...:.|||.|...:  |.:||.   |.|::.:|||..|
Human   195 DTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL---MVLVNYIYFKALW 256

  Fly   239 KFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLP 303
            :.||..:.|..:.|:.:....: ::|||:|:....:..:...|...||.:.|  :....:..:||
Human   257 EKPFISSRTTPKDFYVDENTTV-RVPMMLQDQEHHWYLHDRYLPCSVLRMDY--KGDATVFFILP 318

  Fly   304 KRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDN---EVEVMMPKFVTATDFTLKGVLIQMGI 365
            .:| |:.::...|..       :.|..:.|...:.|   ::|:.:|||..:..:.|..:|.::|.
Human   319 NQG-KMREIEEVLTP-------EMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGF 375

  Fly   366 RDLFDENTANLDRMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFL------- 421
            .|||.: .|:|..::  ..|.|....|...:.|||.||.|.|.|..|:       ||.
Human   376 TDLFSK-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI-------KFFSAQTNRH 432

  Fly   422 ---LNRPFQYMIVEKATGLLLFAGQVRNP 447
               .||||..:|...:|..:||.|:|.:|
Human   433 ILRFNRPFLVVIFSTSTQSVLFLGKVVDP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	100/397 (25%)
SERPINA4	NP_001275961.1	serpinA4_KST	81..463	CDD:381020	102/407 (25%)