Protein Alignment Spn77Ba and SERPINA10

DIOPT Version :10

• Sequence 1: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 124/484 - (25%)
• Similarity: 211/484 - (43%)
• Gaps: 83/484 - (17%)

  Fly     3 KIADCLMLWIPLLLGAIFL---CSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNF 64
            |:...|:|  .:||..::|   .:..||:.:.|             ||....|.|  :|:.:...
Human    42 KVVPSLLL--SVLLAQVWLVPGLAPSPQSPETP-------------APQNQTSRV--VQAPKEEE 89

  Fly    65 DTDVLVS------------------ISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVL 111
            :.:...|                  :::...:|...||::||:   :.:.:.:.|||.:...:..
Human    90 EDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISM---RHDGNMVFSPFGMSLAMTG 151

  Fly   112 LYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITTS-TIEVATLQA--IYTGKGYPIKN 173
            |..|:.|.|..|:|:.|.:........|........|..|.| .:|:...|.  .:..|.:.:|.
Human   152 LMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKE 216

  Fly   174 NYRDAIQNY-NVQPMEVDFYSPDSVIQI-NEDTNRTTRGLIPY---TILPQDVYGAKMFLLSSLY 233
            .:.:..:.| :.:.:.::|.:.....:: |...|:.|||.||.   .|.|:    .|:.|:..:.
Human   217 TFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPE----TKLILVDYIL 277

  Fly   234 FKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAM 298
            |||:|..||:...|..:.|..:..:.| |:|||.....||...: :....:||:|||  |....|
Human   278 FKGKWLTPFDPVFTEVDTFHLDKYKTI-KVPMMYGAGKFASTFD-KNFRCHVLKLPY--QGNATM 338

  Fly   299 IVVLPKRGFKLND-------VANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTL 356
            :|||.:   |:.|       :..:|....||.:..|            .:||..|||.....:.:
Human   339 LVVLME---KMGDHLALEDYLTTDLVETWLRNMKTR------------NMEVFFPKFKLDQKYEM 388

  Fly   357 KGVLIQMGIRDLFDENTANLDRMSS---GLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPP 418
            ..:|.|||||.:|.. .|:|..:|:   .|....|:..|.|.|||:||.|.|...:.:...:.||
Human   389 HELLRQMGIRRIFSP-FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP 452

  Fly   419 KFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            ...::|||.:||.|:.:|:|||.|:|.||
Human   453 VIKVDRPFHFMIYEETSGMLLFLGRVVNP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	107/392 (27%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	109/402 (27%)