Protein Alignment Spn77Ba and SERPINA5

DIOPT Version :10

• Sequence 1: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 98/381 - (25%)
• Similarity: 183/381 - (48%)
• Gaps: 30/381 - (7%)

  Fly    77 QDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVE---DEKLR 138
            :||..||.:.::...  .::....||.|:...|.:|..|:...|:.|:.:.|.:|::   :::|.
Human    46 RDFTFDLYRALASAA--PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELH 108

  Fly   139 GAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFY-SPDSVIQIN 201
            ..::.....||......:::...|::|.....:::.:..|::. |.......:|. |..::.|||
Human   109 RGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQIN 173

  Fly   202 EDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMM 266
            :...:.|:|.| ..:|......|.:.:::.::||.:|:..||...|:|:.|:..| |.:.::|||
Human   174 DYVAKQTKGKI-VDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTS-ETVVRVPMM 236

  Fly   267 VQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAF 331
            .:|..:.|:.: ..|...|:.:||  |.....:.:||..| |:..|.|.|....||   :.|..|
Human   237 SREDQYHYLLD-RNLSCRVVGVPY--QGNATALFILPSEG-KMQQVENGLSEKTLR---KWLKMF 294

  Fly   332 RNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMS--SGLFAKLVVHSTKI 394
            :.|     ::|:.:|||.....:.|:.||..:||.::|..: |:|..:|  |.:....:||...:
Human   295 KKR-----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSH-ADLSGISNHSNIQVSEMVHKAVV 353

  Fly   395 IVDEQGTTAGAVTEAAL---ANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            .|||.||.|.|.|....   :.:....:.:.||||...||:..   :||.|:|..|
Human   354 EVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLGKVNRP 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	97/379 (26%)
SERPINA5	NP_000615.3	serpinA5_PCI	44..406	CDD:381021	97/379 (26%)