Protein Alignment Spn77Ba and SERPINB2

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001137290.1
• Gene: SERPINB2 / 5055
• HGNCID: 8584
• Length: 415
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 115/422 - (27%)
• Similarity: 204/422 - (48%)
• Gaps: 70/422 - (16%)

  Fly    79 FALDLLQRISVEVEKAN--KDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRIN---------- 131
            |||:|.:.::    ||:  ::..:||:|:.|.:.::|.||.|.|.:|:.|.|:.|
Human    11 FALNLFKHLA----KASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTPM 71

  Fly   132 --------------------------VEDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYP 170
                                      ...:|:..:::..||.:|.:|....:.::..::..|...
Human    72 TPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSAS 136

  Fly   171 IKNNYRDAIQN-YNVQPMEVDFY--SPDSVIQINEDTNRTTRGLIPYTILPQ-DVYG-AKMFLLS 230
            .:..|....|. |:.:|..|||.  :.::..:||......|:|.|| .:||: .|.| .:|.|::
Human   137 FREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIP-NLLPEGSVDGDTRMVLVN 200

  Fly   231 SLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMV----QEANFAYVSNVEGLDGYVLELPYG 291
            ::||||:||.||.|.|....||...|.:   :.|:.:    ::.|..|   :|.|...:|||||.
Human   201 AVYFKGKWKTPFEKKLNGLYPFRVNSAQ---RTPVQMMYLREKLNIGY---IEDLKAQILELPYA 259

  Fly   292 TQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAF--RNRASEDNEVEVMMPKFVTATDF 354
            ..  ::|.::||.   ::.||:..|:.|.......:|..:  :::.:|| ||||.:|:|.....:
Human   260 GD--VSMFLLLPD---EIADVSTGLELLESEITYDKLNKWTSKDKMAED-EVEVYIPQFKLEEHY 318

  Fly   355 TLKGVLIQMGIRDLFDENTANLDRMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKA-- 415
            .|:.:|..||:.|.|::..||...||  :.||...|.|...:.|:|:||.|.|.|...:..:.
Human   319 ELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGH 383

  Fly   416 TPPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            ..|:|:.:.||.::|:.|.|..:||.|:..:|
Human   384 GGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	114/417 (27%)
SERPINB2	NP_001137290.1	PAI-2	4..415	CDD:239013	114/420 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.030