Protein Alignment Spn77Ba and SERPINE1

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Alignment Length: 470
• Identity: 112/470 - (23%)
• Similarity: 200/470 - (42%)
• Gaps: 111/470 - (23%)

  Fly     1 MGKIADCLMLWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFD 65
            |.....||:|.:.|:.|.               ..:|.:|          .|.|:|:.|
Human     3 MSPALTCLVLGLALVFGE---------------GSAVHHP----------PSYVAHLAS------ 36

  Fly    66 TDVLVSISQGVQDFALDLLQRISVEVEKANKD--FMISPFSVWSLLVLLYEGSEGETRNQLKKSL 128
                        ||.:    |:..:|.:|:||  .:.||:.|.|:|.:|...:.|||:.|::.::
Human    37 ------------DFGV----RVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAM 85

  Fly   129 RINVEDE----KLRGAYK----VWSSFLNITTSTIEVATLQAIYTGKGYPIKNN--------YRD 177
            ...::|:    .||..||    .|:.        .|::|..||:..:...:...        :|.
Human    86 GFKIDDKGMAPALRHLYKELMGPWNK--------DEISTTDAIFVQRDLKLVQGFMPHFFRLFRS 142

  Fly   178 AIQNYNVQPMEVDFYSPDSVIQINEDTNRT-TRGLIPYTILPQDVYG-------AKMFLLSSLYF 234
            .::       :|||...:....|..|..:| |:|:|      .::.|       .::.|:::|||
Human   143 TVK-------QVDFSEVERARFIINDWVKTHTKGMI------SNLLGKGAVDQLTRLVLVNALYF 194

  Fly   235 KGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGY---VLELPYGTQDRL 296
            .||||.||..:.|....|....|..: .:|||.|...|.| :.....||:   :||||| ..|.|
Human   195 NGQWKTPFPDSSTHRRLFHKSDGSTV-SVPMMAQTNKFNY-TEFTTPDGHYYDILELPY-HGDTL 256

  Fly   297 AMIVVLP-KRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVL 360
            :|.:..| ::...|:.:.|.|.|       |.::.::...:....: :::|||...|:..|:..|
Human   257 SMFIAAPYEKEVPLSALTNILSA-------QLISHWKGNMTRLPRL-LVLPKFSLETEVDLRKPL 313

  Fly   361 IQMGIRDLFDENTANLDRMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLN 423
            ..:|:.|:|.:..|:...:|  ..|.....:...||.|:|.||.|.:.|...::.:..|.:.:::
Human   314 ENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMD 378

  Fly   424 RPFQYMIVEKATGLL 438
            |||.:::....||.|
Human   379 RPFLFVVRHNPTGPL 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	100/396 (25%)
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	103/417 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920