DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	393	Identity:	113/393 - (28%)
Similarity:	192/393 - (48%)	Gaps:	27/393 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVED- 134
            |:|.....|:|:|.::||  ...|:.:...||.|:.|.|.::..|::|.|.:|:.|.|..|.:.
Zfish     3 SLSAANTQFSLNLFKKIS--GGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAH 65

  Fly   135 ---EKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNNY-RDAIQNYNVQPMEVDFY--S 193
               |::...:|.:.|.||...:...::....:|..:.|.:...: .|..:.|:....:|||.  |
Zfish    66 QPVEQIHSNFKKFMSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKS 130

  Fly   194 PDSVIQINEDTNRTTRGLIPYTILPQDVYGA--KMFLLSSLYFKGQWKFPFNKTLTREEPFFSES 256
            .|:.:.||....:.|:..|. .:||.....|  ::.|::::||||.|:..|.|..||:..|....
Zfish   131 EDARVNINTWVEKNTQEKIK-DLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNK 194

  Fly   257 GEVIGKIPMMVQEANF--AYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKAL 319
            .:. ..:.||.|:|.|  .|   :|.:..:||||||..:: |:|:::||.   ::.|....|:.|
Zfish   195 NQT-KPVKMMHQKAEFPSGY---IEEMKSHVLELPYAGKN-LSMLIILPD---EIEDETTGLQKL 251

  Fly   320 GLRPILQRLAAF-RNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSG- 382
            ......::|..: :.......||:|.:|||.|...:.:|.:|:.||:.|:||....||..|||.
Zfish   252 ERALTYEKLMEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSN 316

  Fly   383 -LFAKLVVHSTKIIVDEQGTTAGAVTEA--ALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQV 444
             |.....:|...:.|:|:||.|.|.|.|  .|.....|..|..:.||.:.|....|..:||.|::
Zfish   317 DLVLSKAIHKAFVEVNEEGTEAAAATAAIEKLMCYIPPLSFNADHPFLFFIRHNPTKSILFYGRL 381

  Fly   445 RNP 447
            .:|
Zfish   382 CSP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	110/384 (29%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	111/390 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030