Protein Alignment Spn77Ba and SERPINC1

DIOPT Version :9

• Sequence 1: NP_001287128.1
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 115/506 - (22%)
• Similarity: 195/506 - (38%)
• Gaps: 97/506 - (19%)

  Fly    14 LLLG----------AIFLCSADPQNNQAPLQLSVGNPLTAFTAP----TAFQSGVSHIQSMRSNF 64
            ||:|          .:.:|:|.|::  .|:     ||:..:.:|    |..:.....|....:.
Human    22 LLIGFWDCVTCHGSPVDICTAKPRD--IPM-----NPMCIYRSPEKKATEDEGSEQKIPEATNR- 78

  Fly    65 DTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLR 129
               .:..:|:....||....|.:: :.:..|.:..:||.|:.:...:...|:..:|..||.:..:
Human    79 ---RVWELSKANSRFATTFYQHLA-DSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFK 139

  Fly   130 INVEDEKLRGAYKVWSSFLNI-----TTSTIEVATLQAIYTGKGYPIKNNYRD---AIQNYNVQP 186
            .:...||.......:.:.||.     ...:.::.:...::..|.......|:|   .:....:||
Human   140 FDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQP 204

  Fly   187 MEVDFYSPDSVIQINEDTNRTTRGLIPYTILPQDVYG--AKMFLLSSLYFK-------------- 235
            ::....:..|...||:..:..|.|.|. .::|.:...  ..:.|::::|||
Human   205 LDFKENAEQSRAAINKWVSNKTEGRIT-DVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPL 268

  Fly   236 ---------------------------GQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFA 273
                                       |.||..|:...||:|.|:...||.. ...||.||..|.
Human   269 ALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESC-SASMMYQEGKFR 332

  Fly   274 YVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASED 338
            |....||..  |||||:...| :.|:::|||....|..|...|....|:..|..|        |:
Human   333 YRRVAEGTQ--VLELPFKGDD-ITMVLILPKPEKSLAKVEKELTPEVLQEWLDEL--------EE 386

  Fly   339 NEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRM----SSGLFAKLVVHSTKIIVDEQ 399
            ..:.|.||:|.....|:||..|..||:.|||....:.|..:    ...|:.....|...:.|:|:
Human   387 MMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEE 451

  Fly   400 GTTAGAVTEAALANKATPPK---FLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |:.|.|.|...:|.::..|.   |..||||...|.|.....::|.|:|.||
Human   452 GSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	99/426 (23%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	104/451 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.930