DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpina11

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001008776.1	Gene:	Serpina11 / 362774	RGDID:	1359239	Length:	462	Species:	Rattus norvegicus

Alignment Length:	488	Identity:	118/488 - (24%)
Similarity:	215/488 - (44%)	Gaps:	78/488 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LWIPLLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQ 74
            :|:.||:..:.| ....|.:.|....|:|.|..|           || ||:.   .......::.
  Rat     4 VWLWLLIAELLL-PVHYQPSSAHGDKSLGAPQPA-----------SH-QSLE---PAPAYHKVTP 52

  Fly    75 GVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRG 139
            .:.:|||.|.::::.|:.   .:.:.||.|:.|.:.||..|:..:|:.|:.:||..|:.:.....
  Rat    53 TITNFALRLYKQLAEEIP---GNILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTETPAAD 114

  Fly   140 AYKVWSSF---LNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFYSPDSV-IQ 199
            .::.:.|.   |::.:..:|:....:::..:....:..:.|:.:. |.......:|....:. .|
  Rat   115 IHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATGQQ 179

  Fly   200 INEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIP 264
            ||:...:.|.|.: ...||:......|.||:.::||.:||.||::..||::..|.....:..:||
  Rat   180 INDLVRKQTYGQV-VGCLPEFDRDTLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLRIP 243

  Fly   265 MMVQEANFAYVSNVEGLDGYVLELPY-GTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRL 328
            ||.|:....::.:.|. ...||::.| ||   ..:::|||..| |:..|...|:...||...||.
  Rat   244 MMRQKEMHRFLYDQEA-SCTVLQIEYSGT---ALLLLVLPDPG-KMQQVEAALQPETLRRWGQRF 303

  Fly   329 AAFR-------------NRASE--DNEV-----------------EVMMPKFVTATDFTLKGVLI 361
            ...:             :|.:|  .|.|                 ::.:|:|..:..:.|:.:|.
  Rat   304 LPRKAQAGGAGNGGLHWDRVNEFPQNRVGKLSLKHLQMTQTWSLLDLHLPRFSVSATYNLEEILP 368

  Fly   362 QMGIRDLFDENTANLDRMSSGLFAKL------VVHSTKIIVDEQGTTA----GAVTEAALANKAT 416
            .:|:..|||.. |:|    ||:..:|      |.|...:.::|:||.|    |.:::....|..:
  Rat   369 LVGLSSLFDVE-ADL----SGIMGQLNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMTS 428

  Fly   417 PPKFLLNRPFQYMIVEKATGLLLFAGQVRNPKA 449
            .|....||||..::.|..|..|||.|:|.||.|
  Rat   429 APHAHFNRPFLLLLWEVTTQSLLFLGKVVNPAA 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	100/416 (24%)
Serpina11	NP_001008776.1	alpha-1-antitrypsin_like	53..456	CDD:239011	100/416 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000