DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and serpinb1l4

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_956235.2	Gene:	serpinb1l4 / 335229	ZFINID:	ZDB-GENE-030131-7169	Length:	433	Species:	Danio rerio

Alignment Length:	445	Identity:	111/445 - (24%)
Similarity:	190/445 - (42%)	Gaps:	82/445 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRIN---- 131
            |:|.....|:|:|.::||  ...|:.:...||.|:.|.|.::..|::|.|.:|:.|.|..|
Zfish     3 SLSAANTQFSLNLFKKIS--GGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNPPK 65

  Fly   132 -----------------------------------------------------VEDEKLRGAYKV 143
                                                                 ..:|::..::..
Zfish    66 PGGATPTPAQATQKPKWTCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFNK 130

  Fly   144 WSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPME-VDF--YSPDSVIQINEDTN 205
            ..|.||...:...::....:|..:.|.....|....:.|....:| |||  .|..|.:.||:...
Zfish   131 LMSELNKPGAPYVLSLANRLYGEQTYQFLEKYLSDAKKYYAAGLEKVDFKNKSEASCVNINKWVE 195

  Fly   206 RTTRGLIPYTILPQDVYGA--KMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQ 268
            :.|:..|. .:||.....|  ::.|::::||||.|:..|.|..|::..|.....:. ..:.||.|
Zfish   196 KNTQEKIK-DLLPSGAIDAMTRLVLVNAIYFKGNWEKKFPKEATKDGQFKLNKNQT-KPVKMMHQ 258

  Fly   269 EANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNL----KALGLRPILQRLA 329
            :|.|.:|. :..::..:||||| ....|:|:::||.   ::.|....|    :||....::|...
Zfish   259 KAQFPFVV-IPEINSQILELPY-VGKNLSMLIILPD---EIEDATTGLQKLERALTYEKLMQWTK 318

  Fly   330 AFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSG--LFAKLVVHST 392
            ..|.:     ||:|.:|||.|...:.:|.:|:.||:.|:||....||..|||.  |....|:|..
Zfish   319 VMRQQ-----EVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLVLSKVIHKA 378

  Fly   393 KIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            .:.|:|:||.|.|.|.|.::.:.....|..:.||.:.|...:|..:||.|:..:|
Zfish   379 FVEVNEEGTEAAAATGAVVSIRTLAQIFNADHPFLFFIRHNSTNTILFYGRFCSP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	108/436 (25%)
serpinb1l4	NP_956235.2	SERPIN	4..433	CDD:294093	109/442 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030