DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpine3

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_017171543.1	Gene:	Serpine3 / 319433	MGIID:	2442020	Length:	404	Species:	Mus musculus

Alignment Length:	388	Identity:	106/388 - (27%)
Similarity:	185/388 - (47%)	Gaps:	46/388 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ISQGV----QDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINV 132
            :|:|:    .:|||.|.:  |...|:...:|:|||.||...|.:|..|:.|.|..||..:|...|
Mouse    24 LSEGLWLLKTEFALHLYR--SAAAERNGTNFVISPASVSLSLEILQFGARGNTGWQLAGALGYTV 86

  Fly   133 EDEKLRGAYKVWSSFLNITTST---------IEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPME 188
            :|.:::       .||:...:|         :|:|....:.||..  :...:.:.:..:....:|
Mouse    87 QDPRVK-------EFLHAVYTTRHNSSQGVGMELACTLFMQTGTS--LSPCFVEQVSRWANSSLE 142

  Fly   189 -VDFYSPDS-VIQINEDTNRTTRGLIPYTIL--PQDVYGAKMFLLSSLYFKGQWKFPFNKTLTRE 249
             .||..|:| ..:.::.|:|.:.|..|.:.|  ..|....::.::|::.|:..|:..|:..| :.
Mouse   143 AADFSEPNSTTTEASKVTSRQSTGEGPDSPLWGRADALSTQLSIMSTMTFQSTWQKRFSVVL-QP 206

  Fly   250 EPFFSESGEVIGKIPMM--VQEANFAYVSNVEGLDGYVLELPYGTQDRLA-MIVVLPK-RGFKLN 310
            .||....|.|: ::|.|  |.|.::....:..|.:..||||.|  ..|:| :::|||: :|..|:
Mouse   207 LPFTHAHGLVL-QVPAMHQVAEVSYGQFQDAAGHEIAVLELLY--LGRVASLLLVLPQDKGTPLD 268

  Fly   311 DVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTAN 375
            .:..:|.|..|.....||...|        ::|.:|:|.....|.:|.:|...||.||||...||
Mouse   269 HIEPHLTARVLHLWTTRLKRAR--------MDVFLPRFKIQNQFDVKSILRSWGITDLFDPLKAN 325

  Fly   376 LDRMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATG 436
            |..:|  .|.:...:.|..|:.:.|:||.:.|.|...|..::....|..:|||.:::.|.:||
Mouse   326 LKGISGQDGFYVSQLTHKAKMELSEEGTRSSAATAVLLLRRSRTSAFKADRPFIFLLREHSTG 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	105/385 (27%)
Serpine3	XP_017171543.1	serpin	20..388	CDD:393296	104/386 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920